Tonu Krispin
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Explore the profile of Tonu Krispin including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
114
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Recent Articles
1.
Huik K, Avi R, Uibopuu H, Pauskar M, Margus T, Karki T, et al.
J Acquir Immune Defic Syndr
. 2014 Feb;
66(3):239-44.
PMID: 24508837
Background: The influence of the diversity of CCR5 on HIV susceptibility and disease progression has been clearly demonstrated but how the variability of this gene influences the HIV tropism is...
2.
Avi R, Huik K, Pauskar M, Ustina V, Karki T, Kallas E, et al.
AIDS Res Hum Retroviruses
. 2013 Sep;
30(3):278-83.
PMID: 24025024
The presence of transmitted drug resistance (TDR) in treatment-naive HIV-1-positive subjects is of concern, especially in the countries of the former Soviet Union in which the number of subjects exposed...
3.
Huik K, Avi R, Carrillo A, Harper N, Pauskar M, Sadam M, et al.
PLoS One
. 2013 Aug;
8(7):e70561.
PMID: 23936229
Background: Up to 90% HIV-1 positive intravenous drug users (IDUs) are co-infected with HCV. Although best recognized for its function as a major co-receptor for cell entry of HIV, CC...
4.
Avi R, Huik K, Pauskar M, Ustina V, Karki T, Krispin T, et al.
Scand J Infect Dis
. 2010 Oct;
43(2):122-8.
PMID: 20964489
Human immunodeficiency virus (HIV)-1 transmitted drug resistance in the drug-naïve population is of growing relevance in Estonia, where the number of antiretroviral (ARV) treatment-experienced subjects has been exponentially increasing during...
5.
Avi R, Huik K, Sadam M, Karki T, Krispin T, Ainsalu K, et al.
AIDS Res Hum Retroviruses
. 2010 Sep;
26(10):1109-13.
PMID: 20849300
Natural polymorphisms of HIV-1, often associated with drug resistance, are widely described in protease and reverse transcriptase regions but data on their presence in the integrase region, especially in non-B...
6.
Huik K, Sadam M, Karki T, Avi R, Krispin T, Paap P, et al.
J Infect Dis
. 2010 Jan;
201(5):730-9.
PMID: 20095832
Background: A high copy number of CCL3L1, the most potent human immunodeficiency virus (HIV)-suppressive chemokine, associates with reduced HIV susceptibility. Whether CCL3L1 influences acquisition of multiple blood-borne infections (eg, hepatitis...
7.
Avi R, Huik K, Sadam M, Karki T, Krispin T, Ainsalu K, et al.
J Med Virol
. 2009 Apr;
81(6):953-8.
PMID: 19382254
All non-B HIV-1 subtypes and circulating recombinant forms (CRFs) are characterized by several polymorphisms in protease (PR) region. In addition, in recent years the increasing use of antiretroviral treatment (ART)...
8.
Adojaan M, Molder T, Mannik A, Kivisild T, Villems R, Krispin T, et al.
AIDS Res Hum Retroviruses
. 2007 Mar;
23(2):193-7.
PMID: 17331026
The aim of this survey was to investigate human immunodeficiency virus type 1 (HIV-1) coreceptor, chemokine receptor 5 (CCR5), polymorphism among Estonian HIV-1-infected individuals. Homozygous CCR5Delta32 genotypes have been associated...
9.
Tallo T, Norder H, Tefanova V, Krispin T, Schmidt J, Ilmoja M, et al.
J Med Virol
. 2007 Feb;
79(4):374-82.
PMID: 17311333
During the last decade, there has been a dramatic increase in intravenous drug use in young adults in Estonia with an increased incidence of both hepatitis B and C as...
10.
Adojaan M, Kivisild T, Mannik A, Krispin T, Ustina V, Zilmer K, et al.
J Acquir Immune Defic Syndr
. 2005 Jul;
39(5):598-605.
PMID: 16044014
An earlier study has indicated that a complex recombinant HIV-1 strain dominates the epidemic in Estonia. The objective of this study was to further investigate the molecular epidemiology and genetic...