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Tongyin Zheng

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Articles 8
Citations 53
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Recent Articles
1.
Wake N, Weng S, Zheng T, Wang S, Kirilenko V, Mittal J, et al.
Nat Chem Biol . 2025 Feb; PMID: 39920231
A molecular grammar governing low-complexity prion-like domain phase separation (PS) has identified tyrosine and arginine as primary drivers via aromatic-aromatic and aromatic-arginine interactions. Here we show that additional residues and...
2.
Wake N, Weng S, Zheng T, Wang S, Kirilenko V, Mittal J, et al.
bioRxiv . 2024 Feb; PMID: 38405719
A molecular grammar governing low-complexity prion-like domains phase separation (PS) has been proposed based on mutagenesis experiments that identified tyrosine and arginine as primary drivers of phase separation via aromatic-aromatic...
3.
Wang S, Zheng T, Fawzi N
Biophys J . 2024 Feb; 123(11):1481-1493. PMID: 38297837
Candida albicans, a prominent member of the human microbiome, can make an opportunistic switch from commensal coexistence to pathogenicity accompanied by an epigenetic shift between the white and opaque cell...
4.
Wang S, Zheng T, Fawzi N
bioRxiv . 2023 Nov; PMID: 37986834
, a prominent member of the human microbiome, can make an opportunistic switch from commensal coexistence to pathogenicity accompanied by an epigenetic shift between the white and opaque cell states....
5.
Raymond-Smiedy P, Bucknor B, Yang Y, Zheng T, Castaneda C
Methods Mol Biol . 2022 Oct; 2551:515-541. PMID: 36310223
Liquid-liquid phase separation (LLPS) is hypothesized to be the underlying mechanism for how membraneless organelles or biomolecular condensates form inside both prokaryotic and eukaryotic cells. Protein LLPS is a biophysical...
6.
Zheng T, Galagedera S, Castaneda C
Protein Sci . 2021 May; 30(7):1467-1481. PMID: 34029402
Shuttle protein UBQLN2 functions in protein quality control (PQC) by binding to proteasomal receptors and ubiquitinated substrates via its N-terminal ubiquitin-like (UBL) and C-terminal ubiquitin-associated (UBA) domains, respectively. Between these...
7.
Namitz K, Zheng T, Canning A, Alicea-Velazquez N, Castaneda C, Cosgrove M, et al.
Commun Biol . 2021 Mar; 4(1):398. PMID: 33767358
Accurate gene transcription in eukaryotes depends on isomerization of serine-proline bonds within the carboxy-terminal domain (CTD) of RNA polymerase II. Isomerization is part of the "CTD code" that regulates recruitment...
8.
Zheng T, Yang Y, Castaneda C
Biochem J . 2020 Sep; 477(18):3471-3497. PMID: 32965492
Cells rely on protein homeostasis to maintain proper biological functions. Dysregulation of protein homeostasis contributes to the pathogenesis of many neurodegenerative diseases and cancers. Ubiquilins (UBQLNs) are versatile proteins that...
9.
Yao Q, Yu X, Zheng T, Liu H, Yang Y, Yi P
Spectrochim Acta A Mol Biomol Spectrosc . 2013 Jun; 113:447-51. PMID: 23747387
The interaction of carteolol hydrochloride, to 0.2 mol L(-1) urea-induced bovine serum albumin in aqueous solution has been first investigated by fluorescence spectra and ultraviolet-visible (UV-vis) spectra at pH 7.40....