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Tong Hua

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Articles 18
Citations 179
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Recent Articles
1.
Li Y, Kong E, Ding R, Chu R, Lu J, Deng M, et al.
CNS Neurosci Ther . 2024 Aug; 30(8):e14913. PMID: 39123294
Background: Hyperglycemia-induced neuroinflammation significantly contributes to diabetic neuropathic pain (DNP), but the underlying mechanisms remain unclear. Objective: To investigate the role of Sirt3, a mitochondrial deacetylase, in hyperglycemia-induced neuroinflammation and...
2.
Huang K, Ding R, Lai C, Wang H, Fan X, Chu Y, et al.
Eur J Pharmacol . 2024 Aug; 981:176848. PMID: 39094925
Neuropathic pain (NP) is associated with astrocytes activation induced by nerve injury. Reactive astrocytes, strongly induced by central nervous system damage, can be classified into A1 and A2 types. Vitexin,...
3.
Fan X, Chu R, Jiang X, Ma P, Chu Y, Hua T, et al.
Mol Neurobiol . 2024 Mar; 61(10):8402-8413. PMID: 38509397
Neuropathic pain (NPP) is a common type of chronic pain. Glial cells, including astrocytes (AS), are believed to play an important role in the progression of NPP. AS cells can...
4.
Hua T, Kong E, Zhang H, Lu J, Huang K, Ding R, et al.
Brain Behav Immun . 2024 Feb; 118:101-114. PMID: 38402915
Microglia induced chronic inflammation is the critical pathology of Neuropathic pain (NP). Metabolic reprogramming of macrophage has been intensively reported in various chronic inflammation diseases. However, the metabolic reprogramming of...
5.
Kong E, Hua T, Li J, Li Y, Yang M, Ding R, et al.
Brain . 2024 Feb; 147(7):2552-2565. PMID: 38366606
Chronic varicella zoster virus (VZV) infection induced neuroinflammatory condition is the critical pathology of post-herpetic neuralgia (PHN). The immune escape mechanism of VZV remains elusive. As to mice have no...
6.
Wang J, Yu X, Wang T, Cai W, Hua T, Duan J, et al.
Front Cardiovasc Med . 2023 Jun; 10:1122571. PMID: 37383698
Introduction: Myocardial infarction (MI) is a fatal manifestation of coronary heart disease, and its underlying mechanism is still largely unknown. Lipid levels and composition alterations predict the risk of MI...
7.
Kong E, Li Y, Ma P, Zhang Y, Ding R, Hua T, et al.
J Cell Mol Med . 2023 May; 27(12):1664-1681. PMID: 37132040
The pro-inflammatory phenotype of microglia usually induces neuroinflammatory reactions in neuropathic pain. Glycometabolism shift to glycolysis can promote the pro-inflammatory phenotype transition of microglia. The omics data analysis suggest a...
8.
Wang C, Ma H, Zhang B, Hua T, Wang H, Wang L, et al.
Front Immunol . 2022 Aug; 13:963582. PMID: 35990672
Spinal cord injury (SCI) is a devastating trauma characterized by serious neuroinflammation and permanent neurological dysfunction. However, the molecular mechanism of SCI remains unclear, and few effective medical therapies are...
9.
Hua T, Yang M, Song H, Kong E, Deng M, Li Y, et al.
J Nanobiotechnology . 2022 Jul; 20(1):324. PMID: 35836229
Background: Chronic inflammatory pain significantly reduces the quality of life and lacks effective interventions. In recent years, human umbilical cord mesenchymal stem cells (huc-MSCs)-derived exosomes have been used to relieve...
10.
Kong E, Li Y, Deng M, Hua T, Yang M, Li J, et al.
Front Immunol . 2022 Jun; 13:861290. PMID: 35669777
Neuropathic pain is characterized by hyperalgesia and allodynia. Inflammatory response is conducive to tissue recovery upon nerve injury, but persistent and exaggerated inflammation is detrimental and participates in neuropathic pain....