Tomonobu Takikawa
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Explore the profile of Tomonobu Takikawa including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
106
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Recent Articles
1.
Takahara K, Ouchi N, Takikawa T, Ozaki Y, Fang L, Kawanishi H, et al.
Physiol Rep
. 2025 Jan;
13(3):e70135.
PMID: 39887648
Chronic kidney disease is a life-threatening disease worldwide. PPARα is a crucial transcriptional regulator of lipid metabolism and inflammation. Here, we examine whether a novel selective PPARα modulator, pemafibrate modulates...
2.
Ozaki Y, Ohashi K, Otaka N, Kawanishi H, Takikawa T, Fang L, et al.
Nat Commun
. 2023 Aug;
14(1):4675.
PMID: 37542026
To maintain and restore skeletal muscle mass and function is essential for healthy aging. We have found that myonectin acts as a cardioprotective myokine. Here, we investigate the effect of...
3.
Fang L, Ohashi K, Hayakawa S, Ogawa H, Otaka N, Kawanishi H, et al.
iScience
. 2023 May;
26(5):106591.
PMID: 37250342
Although chronic kidney disease (CKD) is a major health problem worldwide, its underlining mechanism is incompletely understood. We previously identified adipolin as an adipokine which provides benefits for cardiometabolic diseases....
4.
Fang L, Ohashi K, Ogawa H, Otaka N, Kawanishi H, Takikawa T, et al.
Physiol Rep
. 2022 Mar;
10(5):e15218.
PMID: 35262272
Chronic kidney disease (CKD) is an increasing and life-threatening disease worldwide. Recent evidence indicates that blood coagulation factors promote renal dysfunction in CKD patients. Activated factor X (FXa) inhibitors are...
5.
Ozaki Y, Ohashi K, Otaka N, Ogawa H, Kawanishi H, Takikawa T, et al.
Biochem Biophys Res Commun
. 2022 Jan;
593:5-12.
PMID: 35051783
Skeletal muscle atrophy caused by various conditions including aging, nerve damage, and steroid administration, is a serious health problem worldwide. We recently reported that neuron-derived neurotrophic factor (NDNF) functions as...
6.
Fang L, Ohashi K, Otaka N, Ogawa H, Hiramatsu-Ito M, Kawanishi H, et al.
Cardiovasc Res
. 2021 May;
118(6):1597-1610.
PMID: 34051089
Aims: Abdominal aortic aneurysm (AAA) is an increasing and life-threatening disease. Obesity contributes to an increased risk of AAA. Omentin is a circulating adipokine, which is downregulated in obese complications....
7.
Takikawa T, Sumi T, Takahara K, Ohguchi S, Oguri M, Ishii H, et al.
Nagoya J Med Sci
. 2021 Mar;
83(1):93-105.
PMID: 33727741
This study aimed to evaluate the impact of serial changes in nutritional status on 1-year events including all-cause mortality or rehospitalization owing to heart failure (HF) among hospitalized patients with...
8.
Takikawa T, Sumi T, Takahara K, Kawamura Y, Ohguchi S, Oguri M, et al.
Circ Rep
. 2021 Mar;
1(2):87-93.
PMID: 33693118
The purpose of the study was to evaluate the impact of nutritional status on 1-year mortality in hospitalized patients with acute decompensated heart failure (ADHF). We enrolled 457 hospitalized ADHF...
9.
Takikawa T, Ohashi K, Ogawa H, Otaka N, Kawanishi H, Fang L, et al.
PLoS One
. 2020 Dec;
15(12):e0243483.
PMID: 33275602
Background: Myocardial infarction (MI) is a leading cause of death worldwide. We previously identified adipolin, also known as C1q/Tnf-related protein 12, as an anti-inflammatory adipokine with protective features against metabolic...
10.
Kawanishi H, Ohashi K, Ogawa H, Otaka N, Takikawa T, Fang L, et al.
PLoS One
. 2020 Jun;
15(6):e0235362.
PMID: 32584895
Objective: Cardiovascular disease is a leading cause of death worldwide. Obesity-related metabolic disorders including dyslipidemia cause impaired collateralization under ischemic conditions, thereby resulting in exacerbated cardiovascular dysfunction. Pemafibrate is a...