Tomasz Szkudelski
Overview
Explore the profile of Tomasz Szkudelski including associated specialties, affiliations and a list of published articles.
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41
Citations
950
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Recent Articles
1.
Szkudelski T, Szkudelska K
Biochim Biophys Acta Mol Basis Dis
. 2024 Nov;
1871(1):167552.
PMID: 39490940
Heme oxygenase (HO) is an enzyme that catalyzes heme degradation. HO dysfunction is linked to various pathological conditions, including diabetes. Results of animal studies indicate that HO expression and activity...
2.
Szkudelski T, Szkudelska K
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203600
Baicalin is a biologically active flavonoid compound that benefits the organism in various pathological conditions. Rodent studies have shown that this compound effectively alleviates diabetes-related disturbances in models of type...
3.
Okulicz M, Hertig I, Krol E, Szkudelski T
Molecules
. 2022 Sep;
27(17).
PMID: 36080332
Oxidative stress and inflammation play a crucial role in the pathogenesis and progression of diabetes. Currently, there is a growing need to exploit plant-derived bioactive compounds to support conventional therapies....
4.
Szkudelski T, Konieczna K, Szkudelska K
Molecules
. 2022 Aug;
27(16).
PMID: 36014488
Metformin is a biguanide compound commonly applied in humans with type 2 diabetes. The drug affects different tissues, including fat tissue. The direct influence of metformin on cells of fat...
5.
Szkudelska K, Szkudelski T
Biomed Pharmacother
. 2022 Apr;
150:112946.
PMID: 35413601
Betaine (N, N, N-trimethylglycine) is an amino-acid derivative exerting numerous beneficial effects on the organism. This compound is found in human and animal diets but is also endogenously generated. However,...
6.
Okulicz M, Hertig I, Szkudelski T
Toxins (Basel)
. 2022 Jan;
14(1).
PMID: 35050980
Allyl isothiocyanate (AITC), a constituent of Brassica family plants, has been reported to possess a high bioactivity in animal and human cells, showing ambiguous properties from adverse to beneficial ones....
7.
Szkudelski T, Frackowiak K, Szkudelska K
PeerJ
. 2021 Sep;
9:e12092.
PMID: 34557353
Hemin is an activator of heme oxygenase-1 (HO-1), an enzyme catalyzing heme degradation. Up-regulation of HO-1 is observed in response to various pathological conditions. Moreover, pharmacological activation of HO-1 is...
8.
Szkudelska K, Deniziak M, Sassek M, Szkudelski I, Noskowiak W, Szkudelski T
Int J Mol Sci
. 2021 Mar;
22(5).
PMID: 33671110
Resveratrol is a biologically active diphenolic compound exerting multiple beneficial effects in the organism, including anti-diabetic properties. This action is, however, not fully elucidated. In the present study, we examined...
9.
Szkudelska K, Okulicz M, Szkudelski T
Environ Sci Pollut Res Int
. 2021 Jan;
28(18):23301-23309.
PMID: 33447972
Bisphenol A (BPA) is an ubiquitous synthetic chemical exerting numerous adverse effects. Results of rodent studies show that BPA negatively affects adipose tissue. However, the short-term influence of this compound...
10.
Szkudelska K, Okulicz M, Hertig I, Szkudelski T
Biomed Pharmacother
. 2020 Feb;
125:110026.
PMID: 32092822
Type 2 diabetes is associated with inflammatory and oxidative stress. Resveratrol, a naturally occurring diphenolic compound, was shown to improve glycemic control and alleviate metabolic disturbances in Goto-Kakizaki (GK) rats,...