Tomasz L Czarny
Overview
Explore the profile of Tomasz L Czarny including associated specialties, affiliations and a list of published articles.
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6
Citations
468
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Recent Articles
1.
Labana P, Dornan M, Lafreniere M, Czarny T, Brown E, Pezacki J, et al.
Cell Chem Biol
. 2021 Jul;
28(12):1703-1715.e11.
PMID: 34293284
Multi-drug-resistant bacteria present an urgent threat to modern medicine, creating a desperate need for antibiotics with new modes of action. As natural products remain an unsurpassed source for clinically viable...
2.
El-Halfawy O, Czarny T, Flannagan R, Day J, Bozelli Jr J, Kuiack R, et al.
Nat Chem Biol
. 2019 Nov;
16(2):143-149.
PMID: 31768032
Staphylococcus aureus is the leading cause of infections worldwide, and methicillin-resistant strains (MRSA) are emerging. New strategies are urgently needed to overcome this threat. Using a cell-based screen of ~45,000...
3.
Czarny T, Brown E
ACS Infect Dis
. 2016 Sep;
2(7):489-99.
PMID: 27626101
The bacterial cell wall has long been a celebrated target for antibacterial drug discovery due to its critical nature in bacteria and absence in mammalian systems. At the heart of...
4.
Peters J, Colavin A, Shi H, Czarny T, Larson M, Wong S, et al.
Cell
. 2016 May;
165(6):1493-1506.
PMID: 27238023
Essential gene functions underpin the core reactions required for cell viability, but their contributions and relationships are poorly studied in vivo. Using CRISPR interference, we created knockdowns of every essential...
5.
Farha M, Czarny T, Myers C, Worrall L, French S, Conrady D, et al.
Proc Natl Acad Sci U S A
. 2015 Aug;
112(35):11048-53.
PMID: 26283394
Drug combinations are valuable tools for studying biological systems. Although much attention has been given to synergistic interactions in revealing connections between cellular processes, antagonistic interactions can also have tremendous...
6.
Falconer S, Czarny T, Brown E
Nat Chem Biol
. 2011 Jun;
7(7):415-23.
PMID: 21685879
No abstract available.