Tomasz Boczek
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Explore the profile of Tomasz Boczek including associated specialties, affiliations and a list of published articles.
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54
Citations
426
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Recent Articles
1.
Mackiewicz J, Lisek M, Tomczak J, Sakowicz A, Guo F, Boczek T
Front Mol Neurosci
. 2024 Dec;
17:1494160.
PMID: 39654556
Central to the process of axon elongation is the concept of compartmentalized signaling, which involves the A-kinase anchoring protein (AKAP)-dependent organization of signaling pathways within distinct subcellular domains. This spatial...
2.
Tong X, Tong Y, Zheng J, Shi R, Liang H, Li M, et al.
J Neuroinflammation
. 2024 Dec;
21(1):315.
PMID: 39617893
Background: Pyroptosis, a novel form of programmed cell death, has been implicated in neurodegeneration diseases. However, its role in status epilepticus (SE)-a condition characterized by prolonged or repeated seizures-remains inadequately...
3.
Mackiewicz J, Tomczak J, Lisek M, Guo F, Boczek T
Mol Brain
. 2024 Nov;
17(1):85.
PMID: 39578909
Brain-derived neurotrophic factor (BDNF) is known for its potent prosurvival effect. Despite successfully replicating this effect in various clinical and pre-clinical models, the complete characterization of the molecular mechanisms underlying...
4.
Lisek M, Tomczak J, Swiatek J, Kaluza A, Boczek T
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000021
Retinoblastoma, a pediatric ocular malignancy, presents significant challenges in comprehending its molecular underpinnings and targeted therapeutic approaches. The dysregulated activity of histone deacetylases (HDACs) has been associated with retinoblastoma pathogenesis,...
5.
Mackiewicz J, Boczek T
Neural Regen Res
. 2024 May;
20(2):479-480.
PMID: 38819056
No abstract available.
6.
Tomczak J, Mackiewicz J, Lisek M, Kaluza A, Boczek T
Front Mol Neurosci
. 2024 May;
17:1412407.
PMID: 38813437
The complex nature of the retina demands well-organized signaling to uphold signal accuracy and avoid interference, a critical aspect in handling a variety of visual stimuli. A-kinase anchoring proteins (AKAPs),...
7.
Sobolczyk-Prawda M, Boczek T
Curr Protoc
. 2024 May;
4(5):e1048.
PMID: 38752255
Both Ca and protein kinase A (PKA) are multifaceted and ubiquitous signaling molecules, essential for regulating the intricate network of signaling pathways. However, their dynamics within specialized membrane regions are...
8.
Mackiewicz J, Tomczak J, Lisek M, Sakowicz A, Guo F, Boczek T
Mol Neurobiol
. 2024 Apr;
61(11):9383-9401.
PMID: 38639863
Retinal ganglion cells (RGCs), neurons transmitting visual information via the optic nerve, fail to regenerate their axons after injury. The progressive loss of RGC function underlies the pathophysiology of glaucoma...
9.
Lisek M, Tomczak J, Boczek T, Zylinska L
Biomolecules
. 2024 Feb;
14(2).
PMID: 38397420
The dysregulation of intracellular calcium levels is a critical factor in neurodegeneration, leading to the aberrant activation of calcium-dependent processes and, ultimately, cell death. Ca signals vary in magnitude, duration,...
10.
Mackiewicz J, Lisek M, Boczek T
Front Immunol
. 2023 Dec;
14:1281882.
PMID: 38077352
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive loss of cognitive functions. While the exact causes of this debilitating disorder remain elusive, numerous investigations have characterized its...