Tomas Knedlik
Overview
Explore the profile of Tomas Knedlik including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
12
Citations
81
Followers
0
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Recent Articles
11.
Navratil V, Schimer J, Tykvart J, Knedlik T, Vik V, Majer P, et al.
Nucleic Acids Res
. 2016 Sep;
45(2):e10.
PMID: 27679479
Human diseases are often diagnosed by determining levels of relevant enzymes and treated by enzyme inhibitors. We describe an assay suitable for both ultrasensitive enzyme quantification and quantitative inhibitor screening...
12.
Sacha P, Knedlik T, Schimer J, Tykvart J, Parolek J, Navratil V, et al.
Angew Chem Int Ed Engl
. 2016 Jan;
55(7):2356-60.
PMID: 26749427
Antibodies are indispensable tools for biomedicine and anticancer therapy. Nevertheless, their use is compromised by high production costs, limited stability, and difficulty of chemical modification. The design and preparation of...
13.
Knedlik T, Navratil V, Vik V, Pacik D, Sacha P, Konvalinka J
Prostate
. 2014 Mar;
74(7):768-80.
PMID: 24647901
Background: Glutamate carboxypeptidase II (GCPII) is a transmembrane enzyme that cleaves N-acetyl-L-aspartyl-L-glutamate (NAAG) in the brain. GCPII is highly expressed in the prostate and prostate cancer and might be associated...