Tom Turk
Overview
Explore the profile of Tom Turk including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
416
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Recent Articles
1.
Kononenko V, Joukhan A, Bele T, Krizaj I, Kralj S, Turk T, et al.
Biomed Pharmacother
. 2024 Jun;
177:117007.
PMID: 38906020
This study demonstrates the potential of gelatin nanoparticles as a nanodelivery system for antagonists of nicotinic acetylcholine receptors (nAChRs) to improve chemotherapy efficacy and reduce off-target effects. Too often, chemotherapy...
2.
Joukhan A, Kononenko V, Dolenc M, Hocevar M, Turk T, Drobne D
Nanomaterials (Basel)
. 2024 May;
14(9).
PMID: 38727371
Nicotine activates nicotinic acetylcholine receptors (nAChRs), which are overexpressed in numerous cancer types, leading to signaling pathways that increase lung cancer invasiveness and resistance to chemotherapeutic agents. In this study,...
3.
Joukhan A, Kononenko V, Bele T, Dolenc M, Peigneur S, Pinheiro-Junior E, et al.
Mar Drugs
. 2024 Apr;
22(4).
PMID: 38667764
Nicotine binds to nicotinic acetylcholine receptors (nAChRs) that are overexpressed in different cancer cells, promoting tumor growth and resistance to chemotherapy. In this study, we aimed to investigate the potential...
4.
Moodie L, Sepcic K, Turk T, Frangez R, Svenson J
Nat Prod Rep
. 2019 Mar;
36(8):1053-1092.
PMID: 30924818
Covering: Published between 1974 up to 2018Inhibition of cholinesterases is a common approach for the management of several disease states. Most notably, cholinesterase inhibitors are used to alleviate the symptoms...
5.
Berne S, Cemazar M, Frangez R, Juntes P, Kranjc S, Grandic M, et al.
Mar Drugs
. 2018 Oct;
16(10).
PMID: 30282908
The alkylpyridinium polymer APS8, a potent antagonist of α7 nicotinic acetylcholine receptors (nAChRs), selectively induces apoptosis in non-small cell lung cancer cells but not in normal lung fibroblasts. To explore...
6.
Bunc M, Sepcic K, Turk T, Suput D
Pflugers Arch
. 2016 Dec;
440(Suppl 1):R173-R174.
PMID: 28008528
Water soluble polymeric 3-alkylpyridinium salts (poly APS; MW 18900 and 5520 Da) were isolated from the marine sponge Raniera sarai. In vitro it strongly inhibited acetyl cholinesterase (AChE) from different...
7.
Butala M, Sega D, Tomc B, Podlesek Z, Kem W, Kupper F, et al.
Toxicon
. 2015 Oct;
108:32-7.
PMID: 26435341
The heteronemertine Parborlasia corrugatus contains a cytolytic protein, parborlysin, which after extensive purification was found by Edman sequencing to be a mixture of several homologues. To investigate this microheterogeneity and...
8.
Koss D, Robinson L, Mietelska-Porowska A, Gasiorowska A, Sepcic K, Turk T, et al.
Cell Mol Life Sci
. 2015 Jun;
72(23):4613-32.
PMID: 26070304
Patients suffering from tauopathies including frontotemporal dementia (FTD) and Alzheimer's disease (AD) present with intra-neuronal aggregation of microtubule-associated protein Tau. During the disease process, Tau undergoes excessive phosphorylation, dissociates from...
9.
Cajnko M, Mikelj M, Turk T, Podobnik M, Anderluh G
Subcell Biochem
. 2014 May;
80:119-44.
PMID: 24798010
The cell membrane is crucial for protection of the cell from its environment. MACPF/CDC proteins are a large superfamily known to be essential for bacterial pathogenesis and proper functioning of...
10.
Piazza V, Dragic I, Sepcic K, Faimali M, Garaventa F, Turk T, et al.
Mar Drugs
. 2014 Apr;
12(4):1959-76.
PMID: 24699112
Polymeric alkylpyridinium salts (poly-APS) isolated from the Mediterranean marine sponge, Haliclona (Rhizoniera) sarai, effectively inhibit barnacle larva settlement and natural marine biofilm formation through a non-toxic and reversible mechanism. Potential...