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Tom Parks

Explore the profile of Tom Parks including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 749
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Recent Articles
1.
Gourlay-Gudex M, Salama M, Crane R, Whittaker E, Parks T
Arch Dis Child . 2025 Jan; PMID: 39832817
No abstract available.
2.
Hamilton F, Schurz H, Yates T, Gilchrist J, Moller M, Naranbhai V, et al.
Lancet Microbe . 2024 Nov; 6(1):100922. PMID: 39579785
Background: The role of IL-6 responses in human tuberculosis risk is unknown. IL-6 signalling inhibitors, such as tocilizumab, are thought to increase the risk of progression to tuberculosis, and screening...
3.
Mentzer A, Dilthey A, Pollard M, Gurdasani D, Karakoc E, Carstensen T, et al.
Nat Med . 2024 May; 30(5):1384-1394. PMID: 38740997
How human genetic variation contributes to vaccine effectiveness in infants is unclear, and data are limited on these relationships in populations with African ancestries. We undertook genetic analyses of vaccine...
4.
Wirth S, Pulle J, Seo J, Ollberding N, Nakagaayi D, Sable C, et al.
Lancet Glob Health . 2024 Feb; 12(3):e500-e508. PMID: 38365420
Background: Rheumatic heart disease is the largest contributor to cardiac-related mortality in children worldwide. Outcomes in endemic settings after its antecedent illness, acute rheumatic fever, are not well understood. We...
5.
Pulle J, Ndagire E, Atala J, Fall N, Okello E, Oyella L, et al.
Pediatrics . 2024 Feb; 153(3). PMID: 38347821
No abstract available.
6.
Schurz H, Naranbhai V, Yates T, Gilchrist J, Parks T, Dodd P, et al.
Elife . 2024 Jan; 13. PMID: 38224499
The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over 100 genes have been studied as candidates for TB susceptibility, and several variants were identified by genome-wide...
7.
Healy J, Longbottom K, Kent A, Whittaker E, Parks T
Arch Dis Child . 2023 Sep; 109(6):522-523. PMID: 37775145
No abstract available.
8.
Parks T, Narube L, Perman M, Sakumeni K, Fong J, Engelman D, et al.
BMJ Open . 2023 Apr; 13(4):e070629. PMID: 37094887
Objective: To determine population-based rates of non-fatal complications of rheumatic heart disease (RHD). Design: Retrospective cohort study based on multiple sources of routine clinical and administrative data amalgamated by probabilistic...
9.
Hamilton F, Mentzer A, Parks T, Baillie J, Davey Smith G, Ghazal P, et al.
Am J Hum Genet . 2023 Mar; 110(4):691-702. PMID: 36889308
ERAP2 is an aminopeptidase involved in immunological antigen presentation. Genotype data in human samples from before and after the Black Death, an epidemic due to Yersinia pestis, have marked changes...
10.
Hamilton F, Schurz H, Yates T, Gilchrist J, Moller M, Naranbhai V, et al.
medRxiv . 2023 Feb; PMID: 36798349
IL-6 responses are ubiquitous in () infections, but their role in determining human tuberculosis (TB) disease risk is unknown. We used single nucleotide polymorphisms (SNPs) in and near the IL-6...