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Toine C G Egberts

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Articles 193
Citations 2295
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Recent Articles
1.
Lin L, Lucassen M, van der Noort V, Egberts T, Beijnen J, Huitema A
Drug Discov Today . 2025 Mar; 30(3):104324. PMID: 40054765
Before real world data (RWD)-derived external control arms (ECAs) can be applied in clinical trials within the field of oncology, it must be determined whether these ECAs can function as...
2.
Houwen J, Lalmohamed A, Zwaan J, Egberts T, Duyvendak M, Fiolet A, et al.
Eur J Clin Pharmacol . 2025 Mar; PMID: 40053073
Background: Low-dose (0.5 mg/day) colchicine improves cardiovascular outcomes in patients with stable coronary disease. Around 10-15% of these patients simultaneously use anticoagulant therapy, including vitamin-K antagonists (VKAs). In vitro studies...
3.
Van Gelder T, Vergoossen D, Zonnenberg I, Lalmohamed A, Koole-Oostveen M, van Reij E, et al.
Eur J Hosp Pharm . 2025 Jan; PMID: 39863397
Objectives: Critically ill newborn infants often require simultaneous administration of multiple intravenous (IV) solutions through the same catheter lumen, making compatibility of these solutions crucial in neonatal intensive care units...
4.
Smale E, Ottenbros A, van den Bemt B, Heerdink E, Verploegen J, van Zelm R, et al.
JAMA Netw Open . 2024 Oct; 7(10):e2438677. PMID: 39388180
Importance: Medications are associated with substantial environmental outcomes, yet frequently end up being unused by patients. Waste-minimizing interventions, such as redispensing of quality-approved oral anticancer drugs remaining unused by patients...
5.
Smale E, Verkerk E, Heerdink E, Egberts T, van den Bemt B, Bekker C
Explor Res Clin Soc Pharm . 2024 Sep; 15:100493. PMID: 39263193
Background: Minimizing medication waste through the redispensing of oral anticancer drugs (OADs) that were unused by patients provides economic and environmental benefits, but this is not yet universally implemented in...
6.
van de Burgt B, Wasylewicz A, Dullemond B, Jessurun N, Grouls R, Arthur Bouwman R, et al.
JAMIA Open . 2024 Aug; 7(3):ooae070. PMID: 39156048
Objective: Adverse drug reactions (ADRs) are a significant healthcare concern. They are often documented as free text in electronic health records (EHRs), making them challenging to use in clinical decision...
7.
Sadreghaemy M, Gamba M, Bloem L, Egberts T
Pharmacoepidemiol Drug Saf . 2024 Aug; 33(8):e5868. PMID: 39092463
Purpose: In clinical practice, a discrepancy may exist between the prescribed amount of a drug and the commercially available pack sizes in the pharmacy, potentially contributing to drug waste. This...
8.
Bognar T, Garcia-Rosa M, Lalmohamed A, Gungor T, Hauri-Hohl M, Prockop S, et al.
Blood Adv . 2024 Jul; 8(19):5137-5145. PMID: 39074263
Allogeneic hematopoietic cell transplantation (HCT) is a potentially curative treatment strategy for patients with inborn errors of immunities (IEIs). The objective of this study was to assess the optimal busulfan...
9.
Tillemans M, Giezen T, Egberts T, Hooijberg J, Kalisvaart K
Br J Clin Pharmacol . 2024 May; 90(8):1975-1983. PMID: 38747399
Aim: Vitamin B deficiency is common in the elderly population. Standard treatment via intramuscular injections, however, has several disadvantages. Safer and more convenient dosage forms such as intranasal are therefore...
10.
van Dommelen J, Grootjans H, Uijtendaal E, Ruigrok D, Luijk B, van Luin M, et al.
Clin Pharmacokinet . 2024 Apr; 63(5):683-693. PMID: 38581638
Background And Objective: High variability in tacrolimus pharmacokinetics directly after lung transplantation (LuTx) may increase the risk for acute kidney injury (AKI) and transplant rejection. The primary objective was to...