Todd Sulchek
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Explore the profile of Todd Sulchek including associated specialties, affiliations and a list of published articles.
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67
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1493
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Recent Articles
1.
Li H, Harvey D, Dai J, Swingle S, Compton A, Sugali C, et al.
Invest Ophthalmol Vis Sci
. 2025 Feb;
66(2):65.
PMID: 40009371
Purpose: Cross-linked actin networks (CLANs) are prevalent in the glaucomatous trabecular meshwork (TM). We previously developed the GTM3L cell line, which spontaneously forms fluorescently labeled CLANs, by transducing GTM3, a...
2.
Zhong Z, Quinones-Perez M, Dai Z, Juarez V, Bhatia E, Carlson C, et al.
Nat Mater
. 2024 Nov;
24(2):297-311.
PMID: 39506098
Antibodies are produced when naive B cells differentiate into plasma cells within germinal centres (GCs) of lymphoid tissues. Patients with B cell lymphoma on effective immunotherapies exhibit diminished antibody production,...
3.
Li H, Harvey D, Dai J, Swingle S, Compton A, Sugali C, et al.
bioRxiv
. 2024 Sep;
PMID: 39229235
Purpose: Cross-linked actin networks (CLANs) are prevalent in the glaucomatous trabecular meshwork (TM), yet their role in ocular hypertension remains unclear. We used a human TM cell line that spontaneously...
4.
Wong C, Fraticelli Guzman N, Read A, Hedberg-Buenz A, Anderson M, Feola A, et al.
J Biomech
. 2024 Apr;
168:112113.
PMID: 38648717
Atomic force microscopy (AFM) is a valuable tool for assessing mechanical properties of biological samples, but interpretations of measurements on whole tissues can be difficult due to the tissue's highly...
5.
Chrit F, Li P, Sulchek T, Alexeev A
Soft Matter
. 2024 Feb;
20(8):1913-1921.
PMID: 38323349
Numerous applications in medical diagnostics, cell engineering therapy, and biotechnology require the identification and sorting of cells that express desired molecular surface markers. We developed a microfluidic method for high-throughput...
6.
Wong C, Fraticelli Guzman N, Read A, Hedberg-Buenz A, Anderson M, Feola A, et al.
bioRxiv
. 2023 Nov;
PMID: 38014311
Atomic force microscopy (AFM) is a valuable tool for assessing mechanical properties of biological samples, but interpretations of measurements on whole tissues can be difficult due to the tissue's highly...
7.
Yu T, Jhita N, Shankles P, Fedanov A, Kramer N, Raikar S, et al.
Lab Chip
. 2023 Oct;
23(22):4804-4820.
PMID: 37830228
Genetic reprogramming of immune cells to recognize and target tumor cells offers a possibility of long-term cure. Cell therapies, however, lack simple and affordable manufacturing workflows, especially to genetically edit...
8.
Raj A, Ramirez K, Young K, Stone N, Shankles P, Nadeem Rajab Ali M, et al.
Biomicrofluidics
. 2023 Sep;
17(5):054102.
PMID: 37736019
The separation of peripheral blood mononuclear cells (PBMCs) into constituent blood cell types is a vital step to obtain immune cells for autologous cell therapies. The ability to separate PBMCs...
9.
Young K, Xu C, Ahkee K, Mezencev R, Swingle S, Yu T, et al.
iScience
. 2023 Apr;
26(4):106393.
PMID: 37034996
Stiffness has been observed to decrease for many cancer cell types as their metastatic potential increases. Although cell mechanics and metastatic potential are related, the underlying molecular factors associated with...
10.
Strain-dependent elastography of cancer cells reveals heterogeneity and stiffening due to attachment
Xu W, Kabariti S, Young K, Swingle S, Liu A, Sulchek T
J Biomech
. 2023 Mar;
150:111479.
PMID: 36871429
Because cells vary in thickness and in biomechanical properties, the use of a constant force trigger during atomic force microscopy (AFM) stiffness mapping produces a varied nominal strain that can...