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Todd N Eagar

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Recent Articles
1.
Xiong Z, Walsh K, Sneiderman C, Nisnboym M, Hadjipanayis C, Agnihotri S, et al.
Neuro Oncol . 2025 Feb; PMID: 39949048
Background: Individual-level characteristics underlying population-level variation in glioma risk and outcomes remain incompletely understood. Cancer immunosurveillance, host immunity, and some immunotherapies center on the ability of an individual's immune cells...
2.
Fida N, Eagar T, Yun A, Rogers A, Nguyen D, Graviss E, et al.
Clin Transplant . 2024 Feb; 38(2):e15249. PMID: 38369810
Background: Desensitization is one of the strategies to reduce antibodies and facilitate heart transplantation in highly sensitized patients. We describe our center's desensitization experience with combination of plasma cell (PC)...
3.
Harris R, Bush A, Eagar T, Qian J, Greenwood M, Opekun A, et al.
J Pediatr Gastroenterol Nutr . 2023 Jun; 77(3):354-357. PMID: 37347142
Non-caseating granulomas may indicate a more aggressive phenotype of Crohn disease (CD). Genetic associations of granulomatous CD (GCD) may help elucidate disease pathogenesis. Whole-exome sequencing was performed on peripheral blood-derived...
4.
Meinders A, Knight R, Eagar T, Hobeika M, Podder H, Gaber A, et al.
Clin Transplant . 2023 Mar; 37(8):e14963. PMID: 36938669
Introduction: In an effort to maximize living donor kidney utilization, we describe the use of deceased donor vein extension grafts for right-sided living donor kidneys and report our single-center experience...
5.
Roll G, Bray R, Cooper M, Eagar T, Gebel H, Vranic G, et al.
Hum Immunol . 2023 Mar; 84(4):278-285. PMID: 36868898
Although rare, infection and vaccination can result in antibodies to human leukocyte antigens (HLA). We analyzed the effect of SARS-CoV-2 infection or vaccination on HLA antibodies in waitlisted renal transplant...
6.
Vasileiou S, Hill L, Kuvalekar M, Workineh A, Watanabe A, Velazquez Y, et al.
Haematologica . 2022 Nov; 108(7):1840-1850. PMID: 36373249
Defects in T-cell immunity to SARS-CoV-2 have been linked to an increased risk of severe COVID-19 (even after vaccination), persistent viral shedding and the emergence of more virulent viral variants....
7.
Huang H, Yi S, Mobley C, Saharia A, Bhimaraj A, Moore L, et al.
Clin Transplant . 2022 Jan; 36(5):e14600. PMID: 35083796
Response to two doses of a nucleoside-modified messenger ribonucleic acid (mRNA) vaccine was evaluated in a large solid-organ transplant program. mRNA COVID-19 vaccine was administered to transplant candidates and recipients...
8.
Knight R, Loucks-Devos J, Khan N, Nguyen D, Graviss E, Eagar T, et al.
Transplant Proc . 2021 Jul; 53(6):1865-1871. PMID: 34247857
Background: Renal allograft survival is negatively affected by the development of de novo posttransplant donor-specific antibodies (dnDSA). We sought to determine whether treatment with intravenous immunoglobulin (IVIG) could remove or...
9.
Manouchehri N, Hussain R, Cravens P, Esaulova E, Artyomov M, Edelson B, et al.
Proc Natl Acad Sci U S A . 2021 Mar; 118(14). PMID: 33785592
Natalizumab, a humanized monoclonal antibody (mAb) against α4-integrin, reduces the number of dendritic cells (DC) in cerebral perivascular spaces in multiple sclerosis (MS). Selective deletion of α4-integrin in CD11c cells...
10.
Gontu A, Srinivasan S, Salazar E, Surendran Nair M, Nissly R, Greenawalt D, et al.
Commun Biol . 2021 Feb; 4(1):267. PMID: 33627795
Millions of individuals who have recovered from SARS-CoV-2 infection may be eligible to participate in convalescent plasma donor programs, yet the optimal window for donating high neutralizing titer convalescent plasma...