» Authors » Todd Lenvik

Todd Lenvik

Explore the profile of Todd Lenvik including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 2543
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Jiang Y, Jahagirdar B, Reinhardt R, Schwartz R, Keene C, Ortiz-Gonzalez X, et al.
Nature . 2024 Jun; 630(8018):1020. PMID: 38886620
No abstract available.
2.
Davis Z, Felices M, Lenvik T, Badal S, Walker J, Hinderlie P, et al.
Blood Adv . 2021 Feb; 5(4):1069-1080. PMID: 33599743
Expression of programmed cell death protein 1 (PD-1) on natural killer (NK) cells has been difficult to analyze on human NK cells. By testing commercial clones and novel anti-PD-1 reagents,...
3.
Sarhan D, Brandt L, Felices M, Guldevall K, Lenvik T, Hinderlie P, et al.
Blood Adv . 2018 Jun; 2(12):1459-1469. PMID: 29941459
Myelodysplastic syndrome (MDS) is a clonal heterogeneous stem cell disorder driven by multiple genetic and epigenetic alterations resulting in ineffective hematopoiesis. MDS has a high frequency of immune suppressors, including...
4.
Sarhan D, Hippen K, Lemire A, Hying S, Luo X, Lenvik T, et al.
Cancer Immunol Res . 2018 May; 6(7):766-775. PMID: 29784636
Natural killer (NK) cells are capable of fighting viral infections and cancer. However, these responses are inhibited by immune suppressor cells in the tumor microenvironment. Tumor progression promotes the recruitment...
5.
Freund J, May R, Yang E, Li H, McCullen M, Zhang B, et al.
PLoS Biol . 2016 Dec; 14(12):e1002590. PMID: 28033606
[This corrects the article DOI: 10.1371/journal.pbio.1002526.].
6.
Freund J, May R, Yang E, Li H, McCullen M, Zhang B, et al.
PLoS Biol . 2016 Aug; 14(8):e1002526. PMID: 27500644
It has recently been appreciated that NK cells exhibit many features reminiscent of adaptive immune cells. Considerable heterogeneity exists with respect to the ligand specificity of individual NK cells and...
7.
Iizuka Y, Cichocki F, Sieben A, Sforza F, Karim R, Coughlin K, et al.
J Immunol . 2015 Oct; 195(10):4760-70. PMID: 26438524
NK cell's killing is a tightly regulated process under the control of specific cytoskeletal proteins. This includes Wiskott-Aldrich syndrome protein, Wiskott-Aldrich syndrome protein-interacting protein, cofilin, Munc13-4, and nonmuscle myosin IIA...
8.
Romee R, Foley B, Lenvik T, Wang Y, Zhang B, Ankarlo D, et al.
Blood . 2013 Mar; 121(18):3599-608. PMID: 23487023
The Fc receptor CD16 is present on essentially all CD56(dim) peripheral blood natural killer (NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to NK cells, which...
9.
Cichocki F, Lenvik T, Sharma N, Yun G, Anderson S, Miller J
J Immunol . 2010 Jul; 185(4):2009-12. PMID: 20631304
Killer Ig-like receptors (KIRs) are expressed in a variegated, clonally restricted fashion on NK cells and are important determinants of NK cell function. Although silencing of individual KIR genes is...
10.
Bachanova V, McCullar V, Lenvik T, Wangen R, Peterson K, Ankarlo D, et al.
Biol Blood Marrow Transplant . 2009 Jan; 15(2):183-94. PMID: 19167678
Natural Killer (NK) cells are powerful effectors of cytotoxicity against "stressed" cells. They also produce cytokines and chemokines to activate the adaptive immune response. Understanding NK cell development and maturation...