Todd K Leen
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Explore the profile of Todd K Leen including associated specialties, affiliations and a list of published articles.
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12
Citations
115
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Recent Articles
1.
Sourati J, Akcakaya M, Erdogmus D, Leen T, Dy J
IEEE Trans Pattern Anal Mach Intell
. 2017 Sep;
40(8):2023-2029.
PMID: 28858784
The task of labeling samples is demanding and expensive. Active learning aims to generate the smallest possible training data set that results in a classifier with high performance in the...
2.
Leen T, Erdogmus D, Kazmierczak S
Annu Int Conf IEEE Eng Med Biol Soc
. 2013 Feb;
2012:2720-3.
PMID: 23366487
Errors in clinical laboratory tests lead to increased costs and patient risks. Such errors are relatively rare, affecting ∼0.5% of samples. Existing techniques for detecting errors have either far too...
3.
Leen T, Friel R, Nielsen D
Neural Netw
. 2012 Mar;
32:219-28.
PMID: 22418034
On-line machine learning algorithms, many biological spike-timing-dependent plasticity (STDP) learning rules, and stochastic neural dynamics evolve by Markov processes. A complete description of such systems gives the probability densities for...
4.
Leen T, Friel R
Neural Comput
. 2012 Feb;
24(5):1109-46.
PMID: 22295984
Online machine learning rules and many biological spike-timing-dependent plasticity (STDP) learning rules generate jump process Markov chains for the synaptic weights. We give a perturbation expansion for the dynamics that,...
5.
Lu Z, Leen T, Kaye J
Neural Comput
. 2011 Jun;
23(9):2390-420.
PMID: 21671790
We develop several kernel methods for classification of longitudinal data and apply them to detect cognitive decline in the elderly. We first develop mixed-effects models, a type of hierarchical empirical...
6.
Roberts P, Leen T
Front Comput Neurosci
. 2011 Jan;
4:156.
PMID: 21228915
Adaptive sensory processing influences the central nervous system's interpretation of incoming sensory information. One of the functions of this adaptive sensory processing is to allow the nervous system to ignore...
7.
Morris M, Kathawala Q, Leen T, Gorenstein E, Guilak F, Labhard M, et al.
J Med Internet Res
. 2010 May;
12(2):e10.
PMID: 20439251
Background: Emotional awareness and self-regulation are important skills for improving mental health and reducing the risk of cardiovascular disease. Cognitive behavioral therapy can teach these skills but is not widely...
8.
Kazmierczak S, Leen T, Erdogmus D, Carreira-Perpinan M
Clin Chem Lab Med
. 2007 Jun;
45(6):749-52.
PMID: 17579527
Background: The clinical laboratory generates large amounts of patient-specific data. Detection of errors that arise during pre-analytical, analytical, and post-analytical processes is difficult. We performed a pilot study, utilizing a...
9.
van der Merwe R, Leen T, Lu Z, Frolov S, Baptista A
Neural Netw
. 2007 May;
20(4):462-78.
PMID: 17517493
We present neural network surrogates that provide extremely fast and accurate emulation of a large-scale circulation model for the coupled Columbia River, its estuary and near ocean regions. The circulation...
10.
Lu Z, Leen T
Neural Comput
. 2007 Apr;
19(6):1528-67.
PMID: 17444759
While clustering is usually an unsupervised operation, there are circumstances in which we believe (with varying degrees of certainty) that items A and B should be assigned to the same...