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Toby Leslie

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Articles 43
Citations 1066
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Recent Articles
1.
Commons R, Rajasekhar M, Allen E, Yilma D, Chotsiri P, Abreha T, et al.
Lancet Child Adolesc Health . 2024 Sep; 8(11):798-808. PMID: 39332427
Background: Primaquine, the only widely available treatment to prevent relapsing Plasmodium vivax malaria, is produced as 15 mg tablets, and new paediatric formulations are being developed. To inform the optimal...
2.
Verma R, Commons R, Gupta A, Rahi M, Nitika , Bharti P, et al.
BMJ Glob Health . 2023 Dec; 8(12). PMID: 38123228
Background: The optimal dosing of primaquine to prevent relapsing malaria in South Asia remains unclear. We investigated the efficacy and safety of different primaquine regimens to prevent relapse. Methods: A...
3.
Leslie T, Parry C, Ondoa P, Walsh T, Moore C, Poudyal N, et al.
Clin Infect Dis . 2023 Dec; 77(Suppl 7):S497-S499. PMID: 38118008
Antimicrobial resistance (AMR), particularly in low- and middle-income countries, is threatening to undermine advances in health and development. Scarce technical and human resources in these countries limit the collection of...
4.
Joh H, Dolabella B, Early E, Stelling J, Ak G, Upadhyaya M, et al.
Clin Infect Dis . 2023 Dec; 77(Suppl 7):S536-S542. PMID: 38118006
In response to the global threat of antimicrobial resistance (AMR), the Capturing Data on Antimicrobial Resistance Patterns and Trends in Use in Regions of Asia (CAPTURA) project worked with microbiology...
5.
Mehdipour P, Rajasekhar M, Dini S, Zaloumis S, Abreha T, Adam I, et al.
Malar J . 2023 Oct; 22(1):306. PMID: 37817240
Background: Imperfect adherence is a major barrier to effective primaquine radical cure of Plasmodium vivax. This study investigated the effect of reduced adherence on the risk of P. vivax recurrence....
6.
Vesga J, Metras R, Clark M, Ayazi E, Apolloni A, Leslie T, et al.
Vaccine . 2022 Sep; 40(40):5806-5813. PMID: 36058795
Background: Crimean-Congo haemorrhagic fever (CCHF) is a priority emerging pathogen for which a licensed vaccine is not yet available. We aim to assess the feasibility of conducting phase III vaccine...
7.
Vesga J, Clark M, Ayazi E, Apolloni A, Leslie T, Edmunds W, et al.
PLoS Negl Trop Dis . 2022 May; 16(5):e0010454. PMID: 35604940
Background: Crimean-Congo haemorrhagic fever virus (CCHFV) is a highly pathogenic virus for which a safe and effective vaccine is not yet available, despite being considered a priority emerging pathogen. Understanding...
8.
Dickinson S, Chong H, Leslie T, Rowland M, Hansen K, Boyers D
PLoS One . 2021 Nov; 16(11):e0258299. PMID: 34748558
Background: Antimicrobial resistance (AMR) is a global health problem requiring a reduction in inappropriate antibiotic prescribing. Point-of-Care C-Reactive Protein (POCCRP) tests could distinguish between bacterial and non-bacterial causes of fever...
9.
Chandler C, Burchett H, Boyle L, Achonduh O, Mbonye A, DiLiberto D, et al.
Health Syst Reform . 2019 Sep; 2(4):373-388. PMID: 31514719
-Rigorous evidence of "what works" to improve health care is in demand, but methods for the development of interventions have not been scrutinized in the same ways as methods for...
10.
Commons R, Simpson J, Thriemer K, Chu C, Douglas N, Abreha T, et al.
BMC Med . 2019 Aug; 17(1):151. PMID: 31366382
Background: Malaria causes a reduction in haemoglobin that is compounded by primaquine, particularly in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The aim of this study was to determine the relative...