Tobias Zehnder
Overview
Explore the profile of Tobias Zehnder including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
273
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0
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Recent Articles
1.
Ringel A, Szabo Q, Chiariello A, Chudzik K, Schopflin R, Rothe P, et al.
Cell
. 2022 Sep;
185(20):3689-3704.e21.
PMID: 36179666
Regulatory landscapes drive complex developmental gene expression, but it remains unclear how their integrity is maintained when incorporating novel genes and functions during evolution. Here, we investigated how a placental...
2.
Baranasic D, Hortenhuber M, Balwierz P, Zehnder T, Mukarram A, Nepal C, et al.
Nat Genet
. 2022 Jul;
54(7):1037-1050.
PMID: 35789323
Zebrafish, a popular organism for studying embryonic development and for modeling human diseases, has so far lacked a systematic functional annotation program akin to those in other animal models. To...
3.
Sarker B, Zehnder T, Rath S, Horch R, Kneser U, Detsch R, et al.
ACS Biomater Sci Eng
. 2021 Jan;
3(8):1730-1737.
PMID: 33429654
Alginate-based hydrogels are extensively used matrices for cell encapsulation, but they need to be modified to recapitulate chemical, microstructural, and mechanical properties of the native extracellular matrix. Like other cell...
4.
Sarker B, Papageorgiou D, Silva R, Zehnder T, Gul-E-Noor F, Bertmer M, et al.
J Mater Chem B
. 2020 Apr;
2(11):1470-1482.
PMID: 32261366
Microencapsulation of cells by using biodegradable hydrogels offers numerous attractive features for a variety of biomedical applications including tissue engineering. This study highlights the fabrication of microcapsules from an alginate-gelatin...
5.
Chiumia D, Hankele A, Drews B, Zehnder T, Berard J, Giesbertz P, et al.
Anim Reprod Sci
. 2020 Jan;
213:106268.
PMID: 31987321
An alpine environment is unique due to pasture biodiversity, with an abundant content of natural antioxidant polyphenols. The present study investigated the effects of lowland and alpine grazing on the...
6.
Zehnder T, Benner P, Vingron M
BMC Bioinformatics
. 2019 Mar;
20(1):157.
PMID: 30917778
Background: Eukaryotic gene regulation is a complex process comprising the dynamic interaction of enhancers and promoters in order to activate gene expression. In recent years, research in regulatory genomics has...
7.
Zehnder T, Freund T, Demir M, Detsch R, Boccaccini A
Materials (Basel)
. 2017 Aug;
9(11).
PMID: 28774008
Hydrogel optimisation for biofabrication considering shape stability/mechanical properties and cell response is challenging. One approach to tackle this issue is to combine different additive manufacturing techniques, e.g., hot-melt extruded thermoplastics...
8.
Zehnder T, Boccaccini A, Detsch R
Biofabrication
. 2017 Mar;
9(2):025016.
PMID: 28266351
Biofabrication aims to develop functional, biological constructs using automated processes (additive manufacturing, AM) involving different cell types and biomaterials (Groll et al 2016 Biofabrication 13001 1-6). As bone tissue is...
9.
Leite A, Sarker B, Zehnder T, Silva R, Mano J, Boccaccini A
Biofabrication
. 2016 Jul;
8(3):035005.
PMID: 27432012
Alginate dialdehyde-gelatin (ADA-GEL) constructs incorporating bioactive glass nanoparticles (BGNPs) were produced by biofabrication to obtain a grid-like highly-hydrated composite. The material could induce the deposition of an apatite layer upon...
10.
Ivanovska J, Zehnder T, Lennert P, Sarker B, Boccaccini A, Hartmann A, et al.
Tissue Eng Part C Methods
. 2016 Jun;
22(7):708-15.
PMID: 27269631
Hydrogels are an important class of biomaterials as they could mimic the extracellular matrix (ECM). Among the naturally occurring biopolymers, alginate and gelatin are extensively used for many biomedical applications....