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Tobias Woehrle

Explore the profile of Tobias Woehrle including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 819
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Recent Articles
1.
Woehrle T, Pfeiffer F, Mandl M, Sobtzick W, Heitzer J, Krstova A, et al.
MedComm (2020) . 2024 Oct; 5(11):e726. PMID: 39465142
Metal oxide sensor-based electronic nose (E-Nose) technology provides an easy to use method for breath analysis by detection of volatile organic compound (VOC)-induced changes of electrical conductivity. Resulting signal patterns...
2.
Biener I, Mueller T, Lin J, Bao H, Steffen J, Hoerl M, et al.
Transl Psychiatry . 2024 Jan; 14(1):71. PMID: 38296973
The pandemic caused by SARS-CoV-2 impacted health systems globally, creating increased workload and mental stress upon health care workers (HCW). During the first pandemic wave (March to May 2020) in...
3.
Han B, Lv Y, Moser D, Zhou X, Woehrle T, Han L, et al.
EBioMedicine . 2023 Nov; 98:104869. PMID: 37967509
Background: SARS-CoV-2 infects host cells via an ACE2/TMPRSS2 entry mechanism. Monocytes and macrophages, which play a key role during severe COVID-19 express only low or no ACE2, suggesting alternative entry...
4.
Moser D, Feuerecker M, Biere K, Han B, Hoerl M, Schelling G, et al.
Sci Rep . 2022 Sep; 12(1):15485. PMID: 36109525
Secondary infections have been shown to complicate the clinical course and worsen the outcome of critically ill patients. Severe Coronavirus Disease 2019 (COVID-19) may be accompanied by a pronounced cytokine...
5.
Moser D, Biere K, Han B, Hoerl M, Schelling G, Chouker A, et al.
Front Immunol . 2021 Mar; 12:640644. PMID: 33717195
Infection with SARS-CoV-2 can lead to Coronavirus disease-2019 (COVID-19) and result in severe acute respiratory distress syndrome (ARDS). Recent reports indicate an increased rate of fungal coinfections during COVID-19. With...
6.
Woehrle T, Ledderose C, Rink J, Slubowski C, Junger W
Purinergic Signal . 2019 Mar; 15(2):127-137. PMID: 30919205
Previous studies have shown that T cell receptor (TCR) and CD28 coreceptor stimulation involves rapid ATP release, autocrine purinergic feedback via P2X receptors, and mitochondrial ATP synthesis that promote T...
7.
Ledderose C, Hefti M, Chen Y, Bao Y, Seier T, Li L, et al.
Purinergic Signal . 2016 Sep; 12(4):673-685. PMID: 27577957
In neutrophils, adenosine triphosphate (ATP) release and autocrine purinergic signaling regulate coordinated cell motility during chemotaxis. Here, we studied whether similar mechanisms regulate the motility of breast cancer cells. While...
8.
Luchting B, Heyn J, Woehrle T, Rachinger-Adam B, Kreth S, Hinske L, et al.
J Neuroinflammation . 2016 May; 13(1):100. PMID: 27145808
Background: Despite substantial progress, pathogenesis and therapy of chronic pain are still the focus of many investigations. The ATP-gated P2X7 receptor (P2X7R) has previously been shown to play a central...
9.
Ledderose C, Woehrle T, Ledderose S, Strasser K, Seist R, Bao Y, et al.
Purinergic Signal . 2016 Mar; 12(3):439-51. PMID: 27020575
T cells respond to antigen stimulation with the rapid release of cellular ATP, which stimulates an autocrine feedback mechanism that regulates calcium influx through P2X receptors. This autocrine purinergic feedback...
10.
Ledderose C, Bao Y, Ledderose S, Woehrle T, Heinisch M, Yip L, et al.
J Infect Dis . 2015 Jul; 213(3):456-64. PMID: 26150546
T cell suppression in sepsis is a well-known phenomenon; however, the underlying mechanisms are not fully understood. Previous studies have shown that T cell stimulation up-regulates mitochondrial adenosine triphosphate (ATP)...