Tobias W Giessen
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Explore the profile of Tobias W Giessen including associated specialties, affiliations and a list of published articles.
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55
Citations
1030
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Recent Articles
1.
Ubilla-Rodriguez N, Andreas M, Giessen T
bioRxiv
. 2024 Dec;
PMID: 39651212
Encapsulins are self-assembling protein compartments found in prokaryotes and specifically encapsulate dedicated cargo enzymes. The most abundant encapsulin cargo class are Dye-decolorizing Peroxidases (DyPs). It has been previously suggested that...
2.
Andreas M, Giessen T
Nat Commun
. 2024 Nov;
15(1):9715.
PMID: 39521781
Terpenoids are the largest class of natural products, found across all domains of life. One of the most abundant bacterial terpenoids is the volatile odorant 2-methylisoborneol (2-MIB), partially responsible for...
3.
Giessen T
Chembiochem
. 2024 Sep;
25(24):e202400535.
PMID: 39330624
Subcellular compartmentalization is a universal feature of all cells. Spatially distinct compartments, be they lipid- or protein-based, enable cells to optimize local reaction environments, store nutrients, and sequester toxic processes....
4.
Kwon S, Andreas M, Giessen T
ACS Nano
. 2024 Sep;
18(37):25740-25753.
PMID: 39226211
Enzyme nanoreactors are nanoscale compartments consisting of encapsulated enzymes and a selectively permeable barrier. Sequestration and colocalization of enzymes can increase catalytic activity, stability, and longevity, highly desirable features for...
5.
Benisch R, Giessen T
Protein Sci
. 2024 Jul;
33(8):e5129.
PMID: 39073218
Rhodanese-like domains (RLDs) represent a widespread protein family canonically involved in sulfur transfer reactions between diverse donor and acceptor molecules. RLDs mediate these transsulfuration reactions via a transient persulfide intermediate,...
6.
Kwon S, Andreas M, Giessen T
bioRxiv
. 2024 May;
PMID: 38746127
Enzyme nanoreactors are nanoscale compartments consisting of encapsulated enzymes and a selectively permeable barrier. Sequestration and co-localization of enzymes can increase catalytic activity, stability, and longevity, highly desirable features for...
7.
Szyszka T, Andreas M, Lie F, Miller L, Adamson L, Fatehi F, et al.
Proc Natl Acad Sci U S A
. 2024 May;
121(20):e2321260121.
PMID: 38722807
Protein capsids are a widespread form of compartmentalization in nature. Icosahedral symmetry is ubiquitous in capsids derived from spherical viruses, as this geometry maximizes the internal volume that can be...
8.
Andreas M, Giessen T
bioRxiv
. 2024 May;
PMID: 38712110
Terpenoids are the largest class of natural products, found across all domains of life. One of the most abundant bacterial terpenoids is the volatile odorant 2-methylisoborneol (2-MIB), partially responsible for...
9.
Dutcher C, Andreas M, Giessen T
bioRxiv
. 2024 May;
PMID: 38712103
Protein shells or capsids are a widespread form of compartmentalization in nature. Viruses use protein capsids to protect and transport their genomes while many cellular organisms use protein shells for...
10.
Andreas M, Giessen T
Nat Commun
. 2024 Apr;
15(1):3574.
PMID: 38678027
Modified cyclic dipeptides represent a widespread class of secondary metabolites with diverse pharmacological activities, including antibacterial, antifungal, and antitumor. Here, we report the structural characterization of the Streptomyces noursei enzyme...