Tobias Otto
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Explore the profile of Tobias Otto including associated specialties, affiliations and a list of published articles.
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66
Citations
2215
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Recent Articles
11.
Sarang K, Otto T, Rudzinski K, Schaefer T, Grgic I, Nestorowicz K, et al.
Environ Sci Technol
. 2021 Sep;
55(20):13666-13676.
PMID: 34583512
Green plants exposed to abiotic or biotic stress release C-5 and C-6 unsaturated oxygenated hydrocarbons called Green Leaf Volatiles (GLVs). GLVs partition into tropospheric waters and react to form secondary...
12.
Klass A, Otto T, Tegenthoff M, Lissek S
Neurobiol Learn Mem
. 2021 May;
183:107465.
PMID: 34015443
Renewal describes the recovery of an extinguished response if the contexts of extinction and recall differ, highlighting the context dependency of extinction. Studies demonstrated dopaminergic (DA) signalling to be important...
13.
Manns M, Otto T, Salm L
Sci Rep
. 2021 Feb;
11(1):3838.
PMID: 33589698
In situations where the left and right brain sides receive conflicting information that leads to incompatible response options, the brain requires efficient problem-solving mechanisms. This problem is particularly significant in...
14.
Sobhani N, Fassl A, Mondani G, Generali D, Otto T
Cells
. 2021 Feb;
10(2).
PMID: 33535617
Breast cancer (BC) is the most common cause of cancer-related death in women worldwide. Therapies targeting molecular pathways altered in BC had significantly enhanced treatment options for BC over the...
15.
Mohs A, Otto T, Schneider K, Peltzer M, Boekschoten M, Holland C, et al.
J Hepatol
. 2020 Dec;
74(3):638-648.
PMID: 33342543
Background & Aims: In chronic liver diseases, inflammation induces oxidative stress and thus may contribute to the progression of liver injury, fibrosis, and carcinogenesis. The KEAP1/NRF2 axis is a major...
16.
Behroozi M, Helluy X, Strockens F, Gao M, Pusch R, Tabrik S, et al.
Nat Commun
. 2020 Sep;
11(1):4715.
PMID: 32948772
Animal-fMRI is a powerful method to understand neural mechanisms of cognition, but it remains a major challenge to scan actively participating small animals under low-stress conditions. Here, we present an...
17.
Fassl A, Brain C, Abu-Remaileh M, Stukan I, Butter D, Stepien P, et al.
Sci Adv
. 2020 Jul;
6(25):eabb2210.
PMID: 32704543
Inhibitors of cyclin-dependent kinases CDK4 and CDK6 have been approved for treatment of hormone receptor-positive breast cancers. In contrast, triple-negative breast cancers (TNBCs) are resistant to CDK4/6 inhibition. Here, we...
18.
Langer K, Hagedorn B, Stock L, Otto T, Wolf O, Jentsch V
Sci Rep
. 2020 Jul;
10(1):11571.
PMID: 32665617
Emotion regulation is crucial for coping with stressors but in turn can also be influenced by stress. Initial studies provided mixed evidence showing either beneficial or impairing stress effects on...
19.
Michowski W, Chick J, Chu C, Kolodziejczyk A, Wang Y, Suski J, et al.
Mol Cell
. 2020 Apr;
78(3):459-476.e13.
PMID: 32240602
The cyclin-dependent kinase 1 (Cdk1) drives cell division. To uncover additional functions of Cdk1, we generated knockin mice expressing an analog-sensitive version of Cdk1 in place of wild-type Cdk1. In...
20.
Bruggemann M, Xu R, Tilgner A, Kwong K, Mutzel A, Poon H, et al.
Environ Sci Technol
. 2020 Mar;
54(7):3767-3782.
PMID: 32157872
Organosulfates (OSs), also referred to as organic sulfate esters, are well-known and ubiquitous constituents of atmospheric aerosol particles. Commonly, they are assumed to form upon mixing of air masses of...