Tobias M Fischer
Overview
Explore the profile of Tobias M Fischer including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
1156
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Recent Articles
1.
Velanac V, Unterbarnscheidt T, Hinrichs W, Gummert M, Fischer T, Rossner M, et al.
Glia
. 2011 Nov;
60(2):203-17.
PMID: 22052506
Myelin sheath thickness is precisely adjusted to axon caliber, and in the peripheral nervous system, neuregulin 1 (NRG1) type III is a key regulator of this process. It has been...
2.
Djannatian M, Galinski S, Fischer T, Rossner M
Anal Biochem
. 2011 Feb;
412(2):141-52.
PMID: 21295005
G protein-coupled receptors (GPCRs) constitute the largest receptor family in mammals and represent important drug targets. Signaling through GPCRs mediates physiological effects that are strongly dependent on the cellular context....
3.
Botvinnik A, Wichert S, Fischer T, Rossner M
Nat Methods
. 2009 Dec;
7(1):74-80.
PMID: 20010833
The ability to measure multiple cellular signaling events is essential to better understand the underlying complex biological processes that occur in living cells. Microarray-based technologies are now commonly used to...
4.
Brinkmann B, Agarwal A, Sereda M, Garratt A, Muller T, Wende H, et al.
Neuron
. 2008 Sep;
59(4):581-95.
PMID: 18760695
Understanding the control of myelin formation by oligodendrocytes is essential for treating demyelinating diseases. Neuregulin-1 (NRG1) type III, an EGF-like growth factor, is essential for myelination in the PNS. It...
5.
Wehr M, Laage R, Bolz U, Fischer T, Grunewald S, Scheek S, et al.
Nat Methods
. 2006 Oct;
3(12):985-93.
PMID: 17072307
Signaling cascades integrate extracellular stimuli primarily through regulated protein-protein interactions (PPIs). Intracellular signal transduction strictly depends on PPIs occurring at the membrane and in the cytosol. To monitor constitutive and...
6.
Ponomareva O, Fischer T, Lai C, Rimer M
Glia
. 2006 Sep;
54(6):630-7.
PMID: 16944454
Here we show that neuregulin-2 (Nrg-2) alpha- and beta-isoforms can activate acetylcholine receptor (AChR) transcription as surface-attached ligands. More importantly, we demonstrate that Schwann cells that express Nrg-2alpha on their...
7.
Anton E, Ghashghaei H, Weber J, McCann C, Fischer T, Cheung I, et al.
Nat Neurosci
. 2004 Nov;
7(12):1319-28.
PMID: 15543145
Neural progenitor proliferation, differentiation and migration are continually active in the rostral migratory stream of the adult brain. Here, we show that the receptor tyrosine kinase ErbB4 is expressed prominently...
8.
Flames N, Long J, Garratt A, Fischer T, Gassmann M, Birchmeier C, et al.
Neuron
. 2004 Oct;
44(2):251-61.
PMID: 15473965
Most cortical interneurons arise from the subcortical telencephalon, but the molecules that control their migration remain largely unidentified. Here, we show that different isoforms of Neuregulin-1 are expressed in the...
9.
Michailov G, Sereda M, Brinkmann B, Fischer T, Haug B, Birchmeier C, et al.
Science
. 2004 Mar;
304(5671):700-3.
PMID: 15044753
In the nervous system of vertebrates, myelination is essential for rapid and accurate impulse conduction. Myelin thickness depends on axon fiber size. We use mutant and transgenic mouse lines to...