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Tobias Broger

Explore the profile of Tobias Broger including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 921
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Recent Articles
1.
Gaeddert M, Glaser K, Chendi B, Sultanli A, Koeppel L, MacLean E, et al.
J Clin Microbiol . 2024 Oct; 62(11):e0078624. PMID: 39445833
Importance: To our knowledge, this is the first comprehensive systematic review of host blood protein biomarkers for tuberculosis (TB), and we identified promising biomarkers for a TB screening test.
2.
Holtgrewe L, Jain S, Dekova R, Broger T, Isaacs C, Theron G, et al.
J Clin Med . 2024 Oct; 13(19). PMID: 39407954
Rapid and accurate point-of-care (POC) tuberculosis (TB) diagnostics are crucial to bridge the TB diagnostic gap. Leveraging recent advancements in COVID-19 diagnostics, we explored adapting commercially available POC SARS-CoV-2 tests...
3.
Holtgrewe L, Jain S, Dekova R, Broger T, Isaacs C, Nahid P, et al.
medRxiv . 2024 Jul; PMID: 38947060
Introduction: Rapid and accurate point-of-care (POC) tuberculosis (TB) diagnostics are a key priority to close the TB diagnostic gap of 3.1 million people without a diagnosis. Leveraging the recent surge...
4.
Broger T, Marx F, Theron G, Marais B, Nicol M, Kerkhoff A, et al.
Lancet Glob Health . 2024 Jun; 12(7):e1184-e1191. PMID: 38876764
Better access to tuberculosis testing is a key priority for fighting tuberculosis, the leading cause of infectious disease deaths in people. Despite the roll-out of molecular WHO-recommended rapid diagnostics to...
5.
Yerlikaya S, Broger T, Isaacs C, Bell D, Holtgrewe L, Gupta-Wright A, et al.
Infection . 2023 Nov; 52(1):29-42. PMID: 38032537
The COVID-19 pandemic brought diagnostics into the spotlight in an unprecedented way not only for case management but also for population health, surveillance, and monitoring. The industry saw notable levels...
6.
Koeppel L, Denkinger C, Wyss R, Broger T, Chegou N, Dunty J, et al.
J Clin Microbiol . 2023 Sep; 61(10):e0026423. PMID: 37724874
The current four-symptom screen recommended by the World Health Organization (WHO) is widely used as screen to initiate diagnostic testing for active pulmonary tuberculosis (TB), yet the performance is poor...
7.
Broger T, Koeppel L, Huerga H, Miller P, Gupta-Wright A, Blanc F, et al.
Lancet Glob Health . 2023 May; 11(6):e903-e916. PMID: 37202025
Background: Sputum is the most widely used sample to diagnose active tuberculosis, but many people living with HIV are unable to produce sputum. Urine, in contrast, is readily available. We...
8.
Herrmann Y, Lainati F, Castro M, Mwamba C, Kumwenda M, Muyoyeta M, et al.
PLOS Glob Public Health . 2023 Mar; 2(7):e0000672. PMID: 36962216
Widely available tuberculosis (TB) diagnostics use sputum samples. However, many patients, particularly children and patients living with HIV (PLHIV), struggle to provide sputum. Urine diagnostics are a promising approach to...
9.
Yerlikaya S, Holtgrewe L, Broger T, Isaacs C, Nahid P, Cattamanchi A, et al.
BMJ Open . 2023 Feb; 13(2):e065194. PMID: 36754560
Introduction: In 2014, the WHO published high-priority target product profiles (TPPs) for new tuberculosis (TB) diagnostics to align end-user needs with test targets and specifications; nevertheless, no TB test meets...
10.
Dhana A, Hamada Y, Kengne A, Kerkhoff A, Broger T, Denkinger C, et al.
J Infect . 2022 May; 85(1):40-48. PMID: 35588942
Background: WHO recommends urine lateral-flow lipoarabinomannan (LF-LAM) testing with AlereLAM in HIV-positive inpatients only if screening criteria are met. We assessed the performance of WHO screening criteria and alternative screening...