Tirzah Braz Petta Lajus
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Explore the profile of Tirzah Braz Petta Lajus including associated specialties, affiliations and a list of published articles.
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10
Citations
139
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Recent Articles
1.
de Sousa Leal A, de Azevedo Medeiros L, Munoz-Cadavid C, Oliveira R, de Souza Timoteo A, de Oliveira A, et al.
DNA Repair (Amst)
. 2020 Jul;
94:102937.
PMID: 32693352
Xeroderma pigmentosum complementation group A (XPA), is defective in xeroderma pigmentosum patients, causing pre-disposition to skin cancer and neurological abnormalities, which is not well understood. Here, we analyzed the XPA-deficient...
2.
Pinheiro D, de Oliveira A, Coutinho L, Fontes F, de Medeiros Oliveira R, Oliveira T, et al.
Free Radic Biol Med
. 2018 Oct;
130:8-22.
PMID: 30366059
Oxidative stress generated during inflammation is associated with a wide range of pathologies. Resveratrol (RESV) displays anti-inflammatory and antioxidant activities, being a candidate for the development of adjuvant therapies for...
3.
de Souza Timoteo A, Goncalves A, Sales L, Albuquerque B, de Souza J, de Moura P, et al.
Breast Cancer Res Treat
. 2018 Aug;
172(3):637-646.
PMID: 30159786
Purpose: Knowledge about the germline mutational spectrum among Brazilian with hereditary breast and ovarian cancer (HBOC) is limited. Only five studies have performed comprehensive BRCA sequencing, corresponding to 1041 individuals...
4.
Palmero E, Carraro D, Alemar B, Moreira M, Ribeiro-Dos-Santos A, Abe-Sandes K, et al.
Sci Rep
. 2018 Jun;
8(1):9188.
PMID: 29907814
The detection of germline mutations in BRCA1 and BRCA2 is essential to the formulation of clinical management strategies, and in Brazil, there is limited access to these services, mainly due...
5.
de Melo J, de Souza Timoteo A, Braz Petta Lajus T, Brandao J, de Souza-Pinto N, Menck C, et al.
Mutat Res
. 2016 Jan;
784-785:25-33.
PMID: 26811994
Oxidative DNA damage is considered to be a major cause of neurodegeneration and internal tumors observed in syndromes that result from nucleotide excision repair (NER) deficiencies, such as Xeroderma Pigmentosum...
6.
Braz Petta Lajus T
Rev Saude Publica
. 2015 Oct;
49:71.
PMID: 26465663
The Brazilian National Regulatory Agency for Private Health Insurance and Plans has recently published a technical note defining the criteria for the coverage of genetic testing to diagnose hereditary cancer....
7.
Braz Petta Lajus T, Sales R
Gene
. 2015 May;
568(2):215-9.
PMID: 25981591
Germ-line mutation in CDH1 gene is associated with high risk for Hereditary Diffuse Gastric Cancer (HDGC) and Infiltrative Lobular Carcinoma (ILC). Although somatic CDH1 mutations were also detected in ILC...
8.
Fontes F, Pinheiro D, de Oliveira A, de Medeiros Oliveira R, Braz Petta Lajus T, Agnez-Lima L
Mutat Res Rev Mutat Res
. 2015 Mar;
763:246-57.
PMID: 25795123
In recent years, the understanding of how DNA repair contributes to the development of innate and acquired immunity has emerged. The DNA damage incurred during the inflammatory response triggers the...
9.
de Souza Timoteo A, Albuquerque B, Moura P, de Oliveira Ramos C, Fassarela Agnez-Lima L, Walsh T, et al.
Hered Cancer Clin Pract
. 2015 Jan;
13(1):2.
PMID: 25632310
Background: Male breast cancer (MBC) is an uncommon disease that has been the focus of limited research. It is estimated that approximately 10% of men with breast cancer have a...
10.
Gil E, Braz Petta Lajus T, de Moura T, Freire J, da Fernandes A, Leao G, et al.
Mol Cytogenet
. 2013 Sep;
6(1):37.
PMID: 24025689
Background: Cytogenetic studies in Brazilian population about childhood acute lymphoblastic leukemia (ALL), the most common childhood malignancy, are scarce. Moreover, Brazilian race is very heterogeneous and is made by the...