Ting-Yuan Tu
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Explore the profile of Ting-Yuan Tu including associated specialties, affiliations and a list of published articles.
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28
Citations
352
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Recent Articles
11.
Ngo T, Kuo C, Tu T
Biomicrofluidics
. 2023 Jan;
17(1):011501.
PMID: 36647540
Despite several extraordinary improvements in cancer immunotherapy, its therapeutic effectiveness against many distinct cancer types remains mostly limited and requires further study. Different microfluidic-based cancer immunotherapy-on-a-chip (ITOC) systems have been...
12.
The interface stiffness and topographic feature dictate interfacial invasiveness of cancer spheroids
Mao B, Nguyen Thi K, Tang M, Kamm R, Tu T
Biofabrication
. 2023 Jan;
15(1).
PMID: 36594698
During cancer metastasis, tumor cells likely navigate, in a collective manner, discrete tissue spaces comprising inherently heterogeneous extracellular matrix microstructures where interfaces may be frequently encountered. Studies have shown that...
13.
Yang C, Liang C, Tsai S, Wu Y, Liu C, Yang H, et al.
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430445
Multicellular tumor spheroids and tumoroids are considered ideal in vitro models that reflect the features of the tumor microenvironment. Biomimetic components resembling the extracellular matrix form scaffolds to provide structure...
14.
Hsu Y, Chuang H, Tsai K, Tu T, Shyong Y, Kuo C, et al.
Oxid Med Cell Longev
. 2022 Nov;
2022:1380353.
PMID: 36338342
Ligamentum flavum hypertrophy (LFH) is a major cause of lumbar spinal stenosis (LSS). In hypertrophic ligamentum flavum (LF) cells, oxidative stress activates intracellular signaling and induces the expression of inflammatory...
15.
Tu T, Shen Y, Lim S, Wang Y
Front Bioeng Biotechnol
. 2022 May;
10:877480.
PMID: 35586553
Blood vessels are ubiquitous in the human body and play essential roles not only in the delivery of vital oxygen and nutrients but also in many disease implications and drug...
16.
Liao F, Wang Y, Cheng M, Tu T
Polymers (Basel)
. 2022 May;
14(9).
PMID: 35567092
Background: In vitro three-dimensional (3D) hepatic spheroid culture has shown great promise in toxicity testing because it better mimics the cell-cell and cell-matrix interactions found in in vivo conditions than...
17.
Chen Y, Chiu W, Chang C, Wu P, Tu T, Lin H, et al.
RSC Adv
. 2022 May;
8(64):36775-36784.
PMID: 35558959
Chemo-photothermal therapy, which exhibits synergistic effects, is more effective than either of the treatments administered alone because of its superior ability to target and destroy cancer cells. An anti-cancer compound...
18.
Wang L, Chang L, Su G, Chang P, Hsu H, Lee C, et al.
ACS Appl Mater Interfaces
. 2022 Mar;
14(11):13056-13069.
PMID: 35253424
Ineffective site-specific delivery has seriously impeded the efficacy of nanoparticle-based drugs to a disease site. Here, we report the preparation of three different shapes (sphere, scroll, and oblate) to systematically...
19.
Wu K, Kuo C, Tu T
Glob Chall
. 2021 Feb;
5(2):2000056.
PMID: 33552551
3D multicellular tumor spheroids (MCTSs) have recently emerged as a landmark for cancer research due to their inherent traits that are physiologically relevant to primary tumor microenvironments. A facile approach-laser-ablated...
20.
Chuang H, Tsai K, Tsai K, Tu T, Shyong Y, Jou I, et al.
Aging (Albany NY)
. 2020 Nov;
12(23):24168-24183.
PMID: 33223505
The role of oxidative stress in ligamentum flavum (LF) hypertrophy has not been elucidated. We hypothesize that oxidative stress induces inflammatory responses and the subsequent fibrotic processes in LF, via...