Timothy P OBrien
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Explore the profile of Timothy P OBrien including associated specialties, affiliations and a list of published articles.
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15
Citations
403
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Recent Articles
1.
Zhao Y, OBrien T
Genet Res (Camb)
. 2015 Apr;
97:e5.
PMID: 25825238
Development of mammalian lung involves reiterative outgrowth and branching of an epithelial tube into the surrounding mesenchymal bed. Each coordinated growth and branching cycle is driven by reciprocal signalling between...
2.
Welsh I, OBrien T
Dev Biol
. 2009 Sep;
336(1):53-67.
PMID: 19782673
Evolution of facial morphology arises from variation in the activity of developmental regulatory networks that guide the formation of specific craniofacial elements. Importantly, the acquisition of novel morphology must be...
3.
OBrien T, Thompson J, Black P, Becroft D, Clark P, Robinson E, et al.
J Paediatr Child Health
. 2009 Jun;
45(5):291-6.
PMID: 19493122
Aim: The aim of this study is to measure the seroprevalence of cytomegalovirus (CMV) infection in 3.5-year-old children, and identify the determinants of seropositivity. Methods: A total of 1714 children...
4.
Hagarman J, OBrien T
Genesis
. 2009 Apr;
47(6):392-403.
PMID: 19391113
The piebald deletion complex is a set of overlapping chromosomal deficiencies on distal mouse chromosome 14. We surveyed the functional genetic content of the piebald deletion region in an essential...
5.
Madenjian C, Wang C, OBrien T, Holuszko M, Ogilvie L, Stickel R
Fish Physiol Biochem
. 2008 Nov;
36(1):45-53.
PMID: 18979219
Walleye (Sander vitreus) is an important game fish throughout much of North America. We evaluated the performance of the Wisconsin bioenergetics model for walleye in the laboratory. Walleyes were fed...
6.
Welsh I, Hagge-Greenberg A, OBrien T
Mech Dev
. 2007 Aug;
124(9-10):746-61.
PMID: 17693063
The formation of the palate involves the coordinated outgrowth, elevation and midline fusion of bilateral shelves leading to the separation of the oral and nasal cavities. Reciprocal signaling between adjacent...
7.
Han L, Figueiredo M, Berghorn K, Iwata T, Clark-Campbell P, Welsh I, et al.
Endocrinology
. 2006 Nov;
148(3):1246-54.
PMID: 17110422
Dlx3, a homeodomain transcription factor, is essential for placental development in the mouse. The Dlx3(-/-) mouse embryo dies at embryonic d 9.5-10 putatively due to placental failure. To develop a...
8.
Shopland L, Lynch C, Peterson K, Thornton K, Kepper N, von Hase J, et al.
J Cell Biol
. 2006 Jul;
174(1):27-38.
PMID: 16818717
Specific mammalian genes functionally and dynamically associate together within the nucleus. Yet, how an array of many genes along the chromosome sequence can be spatially organized and folded together is...
9.
Burgess R, Peterson K, Johnson M, Roix J, Welsh I, OBrien T
Mol Cell Biol
. 2004 Jan;
24(3):1096-105.
PMID: 14729956
Genetic studies using a set of overlapping deletions centered at the piebald locus on distal mouse chromosome 14 have defined a genomic region associated with respiratory distress and lethality at...
10.
OBrien T, Frankel W
J Physiol
. 2003 Dec;
554(Pt 1):13-21.
PMID: 14678486
The study of genetic variation in mice offers a powerful experimental platform for understanding gene function. Complex trait analysis, gene-targeting and gene-trapping technologies, as well as insertional and chemical mutagenesis...