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Timothy M Williams

Explore the profile of Timothy M Williams including associated specialties, affiliations and a list of published articles. Areas
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11.
Williams T, Wise A, Alikhan M, Layton D, Ricardo S
Cytometry A . 2013 Nov; 85(3):256-67. PMID: 24265261
Polychromatic flow cytometry is a powerful tool for assessing populations of cells in the kidney through times of homeostasis, disease and tissue remodeling. In particular, macrophages have been identified as...
12.
Jones C, Williams T, Walker K, Dickinson H, Sakkal S, Rumballe B, et al.
Respir Res . 2013 Apr; 14:41. PMID: 23560845
Background: Macrophages are traditionally associated with inflammation and host defence, however a greater understanding of macrophage heterogeneity is revealing their essential roles in non-immune functions such as development, homeostasis and...
13.
Alikhan M, Jones C, Williams T, Beckhouse A, Fletcher A, Kett M, et al.
Am J Pathol . 2011 Jul; 179(3):1243-56. PMID: 21762674
Colony-stimulating factor (CSF)-1 controls the survival, proliferation, and differentiation of macrophages, which are recognized as scavengers and agents of the innate and the acquired immune systems. Because of their plasticity,...
14.
Williams T, Little M, Ricardo S
Semin Nephrol . 2010 Jul; 30(3):255-67. PMID: 20620670
Macrophages have long been regarded as classic mediators of innate immunity because of their production of proinflammatory cytokines and their ability to induce apoptotic cell death. As a result of...
15.
Costa-Pereira A, Hermanns H, Isharc H, Williams T, Watling D, Arulampalam V, et al.
J Immunol . 2005 Oct; 175(9):5958-65. PMID: 16237089
Activation of STAT1 and the IFN-gamma response are thought to be mediated exclusively through the Y440 motif of the human IFNGR1 receptor subunit. Contrary to this accepted dogma, here it...
16.
Costa-Pereira A, Williams T, Strobl B, Watling D, Briscoe J, Kerr I
J Virol . 2002 Aug; 76(18):9060-8. PMID: 12186889
A role for alpha/beta interferon (IFN-alpha/beta) in the IFN-gamma antiviral response has long been suggested. Accordingly, possible roles for autocrine or double-stranded-RNA (dsRNA)-induced IFN-alpha/beta in the IFN-gamma response were investigated....