Timothy J Whelan
Overview
Explore the profile of Timothy J Whelan including associated specialties, affiliations and a list of published articles.
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92
Citations
5239
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Recent Articles
11.
Whelan T, Parpia S, Levine M
N Engl J Med
. 2023 Nov;
389(18):1727-1728.
PMID: 37913519
No abstract available.
12.
Goodwin P, Chen B, Gelmon K, Whelan T, Ennis M, Lemieux J, et al.
J Clin Oncol
. 2023 Sep;
41(35):5356-5362.
PMID: 37695982
JCO Metformin has been associated with lower cancer risk in epidemiologic and preclinical research. In the MA.32 randomized adjuvant breast cancer trial, metformin ( placebo) did not affect invasive disease-free...
13.
Nielsen T, Leung S, Riaz N, Mulligan A, Kos Z, Bane A, et al.
Histopathology
. 2023 Aug;
83(6):903-911.
PMID: 37609778
Aims: The LUMINA trial demonstrated a very low local recurrence rate in women ≥55 years with low-risk luminal A breast cancer (defined as grade I-II, T1N0, hormone receptor positive, HER2...
14.
Whelan T, Smith S, Parpia S, Fyles A, Bane A, Liu F, et al.
N Engl J Med
. 2023 Aug;
389(7):612-619.
PMID: 37585627
Background: Adjuvant radiotherapy is prescribed after breast-conserving surgery to reduce the risk of local recurrence. However, radiotherapy is inconvenient, costly, and associated with both short-term and long-term side effects. Clinicopathologic...
15.
Hershman D, Chen B, Sathe C, Parulekar W, Lemieux J, Ligibel J, et al.
Breast Cancer Res Treat
. 2023 May;
200(1):93-102.
PMID: 37157006
Background: The MA32 study investigated whether 5 years of metformin (versus placebo) improves invasive disease-free survival in early-stage breast cancer (BC). Non-adherence to endocrine therapy (ET) and medications for chronic...
16.
Riaz N, Jeen T, Whelan T, Nielsen T
Cancers (Basel)
. 2023 Feb;
15(4).
PMID: 36831598
Adjuvant whole breast irradiation after breast-conserving surgery is a well-established treatment standard for early invasive breast cancer. Screening, early diagnosis, refinement in surgical techniques, the knowledge of new and specific...
17.
Swaminath A, Wierzbicki M, Parpia S, Kundapur V, Faria S, Ahmed N, et al.
Clin Transl Radiat Oncol
. 2022 Oct;
37:145-152.
PMID: 36275452
Purpose: To report on the Stereotactic Body Radiation Therapy (SBRT) credentialing experience during the Phase III Ontario Clinical Oncology Group (OCOG) LUSTRE trial for stage I non-small cell lung cancer....
18.
Goldberg M, Bridhikitti J, Khan A, McGale P, Whelan T
Int J Radiat Oncol Biol Phys
. 2022 Sep;
115(1):60-72.
PMID: 36155214
Purpose: Partial breast irradiation (PBI) is the delivery of radiation therapy (RT) limited to the tumor bed after breast conserving surgery. The results of recent trials of PBI compared with...
19.
Chua B, Link E, Kunkler I, Whelan T, Westenberg A, Gruber G, et al.
Lancet
. 2022 Aug;
400(10350):431-440.
PMID: 35934006
Background: Whole breast irradiation (WBI) after conservative surgery for ductal carcinoma in situ (DCIS) reduces local recurrence. We investigated whether a tumour bed boost after WBI improved outcomes, and examined...
20.
Goodwin P, Chen B, Gelmon K, Whelan T, Ennis M, Lemieux J, et al.
JAMA
. 2022 May;
327(20):1963-1973.
PMID: 35608580
Importance: Metformin, a biguanide commonly used to treat type 2 diabetes, has been associated with potential beneficial effects across breast cancer subtypes in observational and preclinical studies. Objective: To determine...