Tim Lin
Overview
Explore the profile of Tim Lin including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
269
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0
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Recent Articles
1.
Neul J, Percy A, Benke T, Berry-Kravis E, Glaze D, Marsh E, et al.
Nat Med
. 2023 Jun;
29(6):1468-1475.
PMID: 37291210
Rett syndrome is a rare, genetic neurodevelopmental disorder. Trofinetide is a synthetic analog of glycine-proline-glutamate, the N-terminal tripeptide of the insulin-like growth factor 1 protein, and has demonstrated clinical benefit...
2.
Dirks B, Fava M, Atkinson S, Joyce M, Thase M, Howell B, et al.
Psychopharmacol Bull
. 2022 Nov;
52(4):8-30.
PMID: 36339271
Objective: In a phase 2 study, pimavanserin demonstrated efficacy as adjunctive treatment for major depressive disorder (MDD). Subsequently, two phase 3 studies (NCT03968159 in the US; NCT03999918 in Europe) were...
3.
Chertow G, Pergola P, Farag Y, Agarwal R, Arnold S, Bako G, et al.
N Engl J Med
. 2021 Apr;
384(17):1589-1600.
PMID: 33913637
Background: Vadadustat is an oral hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, a class of drugs that stabilize HIF and stimulate erythropoietin and red-cell production. Methods: In two phase 3, randomized,...
4.
Chertow G, Pergola P, Agarwal R, Block G, Farag Y, Jardine A, et al.
Am Heart J
. 2020 Nov;
235:1-11.
PMID: 33129989
Current clinical practice guidelines for anemia management in non-dialysis-dependent chronic kidney disease (NDD-CKD) recommend the use of erythropoiesis-stimulating agents (ESAs) as standard of care. Vadadustat, an investigational oral hypoxia-inducible factor...
5.
Gouya L, Ventura P, Balwani M, Bissell D, Rees D, Stolzel U, et al.
Hepatology
. 2019 Sep;
71(5):1546-1558.
PMID: 31512765
Background And Aims: Acute hepatic porphyria comprises a group of rare genetic diseases caused by mutations in genes involved in heme biosynthesis. Patients can experience acute neurovisceral attacks, debilitating chronic...
6.
Guerci B, Trautmann M, Lin T, Hardy E, Mudaliar S
Diabetes Obes Metab
. 2018 Dec;
21(4):1049-1053.
PMID: 30520252
This post-hoc analysis of the DURATION-3 study aimed to identify factors associated with sustained glycaemic response with exenatide once weekly (QW) or insulin glargine (IG) among patients with type 2...
7.
Wang J, Ban M, Zou G, Cao H, Lin T, Kennedy B, et al.
Hum Mol Genet
. 2008 Jul;
17(18):2894-9.
PMID: 18596051
Recent genome-wide association (GWA) studies have identified new genetic determinants of complex quantitative traits, including plasma triglyceride (TG). We hypothesized that common variants associated with mild TG variation identified in...