Tim A Rand
Overview
Explore the profile of Tim A Rand including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
1050
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lau D, Khare S, Stein M, Jain P, Gao Y, BenTaieb A, et al.
Nat Commun
. 2022 Jul;
13(1):4053.
PMID: 35831288
The efficacy of immune checkpoint blockade (ICB) varies greatly among metastatic non-small cell lung cancer (NSCLC) patients. Loss of heterozygosity at the HLA-I locus (HLA-LOH) has been identified as an...
2.
Larsen B, Kannan M, Langer L, Leibowitz B, BenTaieb A, Cancino A, et al.
Cell Rep
. 2021 Jul;
36(4):109429.
PMID: 34320344
Patient-derived tumor organoids (TOs) are emerging as high-fidelity models to study cancer biology and develop novel precision medicine therapeutics. However, utilizing TOs for systems-biology-based approaches has been limited by a...
3.
Rand T, Sutou K, Tanabe K, Jeong D, Nomura M, Kitaoka F, et al.
Cell Rep
. 2018 Apr;
23(2):361-375.
PMID: 29641997
Here, we report that MYC rescues early human cells undergoing reprogramming from a proliferation pause induced by OCT3/4, SOX2, and KLF4 (OSK). We identified ESRG as a marker of early...
4.
Sugiyama H, Takahashi K, Yamamoto T, Iwasaki M, Narita M, Nakamura M, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
114(2):340-345.
PMID: 28003464
Novel APOBEC1 target 1 (Nat1) (also known as "p97," "Dap5," and "Eif4g2") is a ubiquitously expressed cytoplasmic protein that is homologous to the C-terminal two thirds of eukaryotic translation initiation...
5.
Kime C, Mandegar M, Srivastava D, Yamanaka S, Conklin B, Rand T
Curr Protoc Hum Genet
. 2016 Jan;
88:21.4.1-21.4.23.
PMID: 26724721
Human pluripotent stem cells (hPS cells) are rapidly emerging as a powerful tool for biomedical discovery. The advent of human induced pluripotent stem cells (hiPS cells) with human embryonic stem...
6.
Kime C, Rand T, Ivey K, Srivastava D, Yamanaka S, Tomoda K
Curr Protoc Hum Genet
. 2015 Oct;
87:21.2.1-21.2.21.
PMID: 26439714
The advent of induced pluripotent stem (iPS) cell technology has revolutionized biomedicine and basic research by yielding cells with embryonic stem (ES) cell-like properties. The use of iPS-derived cells for...
7.
Worringer K, Rand T, Hayashi Y, Sami S, Takahashi K, Tanabe K, et al.
Cell Stem Cell
. 2013 Nov;
14(1):40-52.
PMID: 24239284
Reprogramming differentiated cells into induced pluripotent stem cells (iPSCs) promotes a broad array of cellular changes. Here we show that the let-7 family of microRNAs acts as an inhibitory influence...
8.
Rand T, Petersen S, Du F, Wang X
Cell
. 2005 Nov;
123(4):621-9.
PMID: 16271385
The mRNA-cleavage step of RNA interference is mediated by an endonuclease, Argonaute2 (Ago2), within the RNA-induced silencing complex (RISC). Ago2 uses one strand of the small interfering (si) RNA duplex...
9.
Rand T, Ginalski K, Grishin N, Wang X
Proc Natl Acad Sci U S A
. 2004 Sep;
101(40):14385-9.
PMID: 15452342
RNA interference is carried out by the small double-stranded RNA-induced silencing complex (RISC). The RISC-bound small RNA guides the RISC complex to identify and cleave mRNAs with complementary sequences. The...
10.
Liu Q, Rand T, Kalidas S, Du F, Kim H, Smith D, et al.
Science
. 2003 Sep;
301(5641):1921-5.
PMID: 14512631
The RNA interference (RNAi) pathway is initiated by processing long double-stranded RNA into small interfering RNA (siRNA). The siRNA-generating enzyme was purified from Drosophila S2cells and consists of two stoichiometric...