Tibor Harkany
Overview
Explore the profile of Tibor Harkany including associated specialties, affiliations and a list of published articles.
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154
Citations
5982
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Recent Articles
21.
Zambon A, Rico L, Herman M, Gundacker A, Telalovic A, Hartenberger L, et al.
Mol Psychiatry
. 2022 May;
29(4):859-873.
PMID: 35581295
Immune activation is one of the most common complications during pregnancy, predominantly evoked by viral infections. Nevertheless, how immune activation affects mother-offspring relationships postpartum remains unknown. Here, by using the...
22.
Hevesi Z, Gerges D, Kapps S, Freire R, Schmidt S, Pollak D, et al.
Vaccines (Basel)
. 2022 Apr;
10(4).
PMID: 35455265
First-generation vaccines against SARS-CoV-2 do not provide adequate immune protection. Therefore, we engineered a divalent gene construct combining the receptor-binding domain (RBD) of the spike protein and the immunodominant region...
23.
Ahmed M, Kaur N, Cheng Q, Shanabrough M, Tretiakov E, Harkany T, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(16):e2200476119.
PMID: 35412887
Augmentor α and β (Augα and Augβ) are newly discovered ligands of the receptor tyrosine kinases Alk and Ltk. Augα functions as a dimeric ligand that binds with high affinity...
24.
Smedler E, Louhivuori L, Romanov R, Masini D, Dehnisch Ellstrom I, Wang C, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(7).
PMID: 35135875
The L-type voltage-gated Ca channel gene is a risk gene for various psychiatric conditions, including schizophrenia and bipolar disorder. However, the cellular mechanism by which contributes to psychiatric disorders has...
25.
Steffens S, Bakker J, Glat M, Keimpema E, Pollak D, Hokfelt T, et al.
Eur J Neurosci
. 2022 Jan;
55(3):725-732.
PMID: 34978111
Experimental investigation of early postnatal brain development in infant mice (<postnatal day 10) is challenging because of the rapid expansion of their brain volume and the fragility of cranial bones....
26.
Keimpema E, Di Marzo V, Harkany T
Science
. 2021 Dec;
374(6574):1449-1450.
PMID: 34914498
Mechanistic insights into cannabinoid signaling could improve therapeutic applications.
27.
Saucisse N, Mazier W, Simon V, Binder E, Catania C, Bellocchio L, et al.
Cell Rep
. 2021 Oct;
37(2):109800.
PMID: 34644574
Hypothalamic pro-opiomelanocortin (POMC) neurons are known to trigger satiety. However, these neuronal cells encompass heterogeneous subpopulations that release γ-aminobutyric acid (GABA), glutamate, or both neurotransmitters, whose functions are poorly defined....
28.
Harkany T, Cinquina V
Cannabis Cannabinoid Res
. 2021 Oct;
6(5):381-388.
PMID: 34619043
The endocannabinoid system is chiefly recognized as a homeostatic regulator of synaptic neurotransmission, primarily through the modulation of presynaptic CB cannabinoid neurons. Accordingly, the use of plant-derived cannabinoids received significant...
29.
Patthy A, Murai J, Hanics J, Pinter A, Zahola P, Hokfelt T, et al.
J Clin Med
. 2021 Apr;
10(8).
PMID: 33917176
Alzheimer's disease (AD) is a devastating neurodegenerative disorder as yet without effective therapy. Symptoms of this disorder typically reflect cortical malfunction with local neurohistopathology, which biased investigators to search for...
30.
Tortoriello G, Beiersdorf J, Romani S, Williams G, Cameron G, Mackie K, et al.
Cannabis Cannabinoid Res
. 2021 Apr;
6(2):119-136.
PMID: 33912677
In mammals, sn-1-diacylglycerol lipases (DAGL) generate 2-arachidonoylglycerol (2-AG) that, as the major endocannabinoid, modulates synaptic neurotransmission by acting on CB1 cannabinoid receptors (CBR). Even though the insect genome codes for...