Tian-Qi Chen
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Explore the profile of Tian-Qi Chen including associated specialties, affiliations and a list of published articles.
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20
Citations
542
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Recent Articles
1.
Sun Y, Zhu S, Chen X, Pan Q, An Y, Chen T, et al.
Mol Cell
. 2024 Nov;
84(24):4878-4895.e10.
PMID: 39579766
Liquid-to-solid phase transition of proteins with prion-like domains (PLDs) has been associated with neurodegenerative diseases and aging. High protein concentration is one important aspect triggering the transition; however, several prion-like...
2.
Zhou Y, Dong W, Qiu Y, Shao K, Zhang Z, Yao J, et al.
Neuropharmacology
. 2024 Jun;
257:110032.
PMID: 38852839
The full mechanism of action of propofol, a commonly administered intravenous anesthetic drug in clinical practice, remains elusive. The focus of this study was the role of GABAergic neurons which...
3.
Chen X, Qian W, Chen T, Shao L, Zhang W, Zhang S
Se Pu
. 2024 Jun;
42(6):572-580.
PMID: 38845518
Perfluorooctanoic acid (PFOA) is a persistent contaminant with detrimental effects on the natural environment. This persistence leads to potential enrichment and osmotic transfer, which can affect normal circulation in the...
4.
Chen T, Huang H, Zhu S, Chen X, Pu K, Wang D, et al.
Exp Hematol Oncol
. 2024 Feb;
13(1):18.
PMID: 38374003
Background: Mixed-lineage leukemia (MLL) fusion gene caused by chromosomal rearrangement is a dominant oncogenic driver in leukemia. Due to having diverse MLL rearrangements and complex characteristics, MLL leukemia treated by...
5.
Sun J, Hu B, Chen T, Chen Z, Shang Y, Li Y, et al.
Brain Imaging Behav
. 2023 Mar;
17(3):329-342.
PMID: 36899209
Internet addiction (IA) is a growing social concern and has been intensively studied in recent years. Previous imaging studies have shown that IA may impair brain structure and function, but...
6.
Liu J, Sun J, Hu H, Wang H, Kang Y, Chen T, et al.
Psychiatry Investig
. 2023 Feb;
20(1):69-74.
PMID: 36721888
A growing number of neuroimaging studies have revealed abnormal brain structural and functional alterations in subjects with internet addiction (IA), however, with conflicting conclusions. We plan to conduct a systematic...
7.
Zeng Z, Pan Q, Sun Y, Huang H, Chen X, Chen T, et al.
EMBO Rep
. 2023 Jan;
24(3):e55762.
PMID: 36597993
N -Methyladenosine (m A) is an important RNA modification catalyzed by methyltransferase-like 3 (METTL3) and METTL14. m A homeostasis mediated by the methyltransferase (MTase) complex plays key roles in various...
8.
Huang W, Sun Y, Pan Q, Fang K, Chen X, Zeng Z, et al.
Cell Discov
. 2022 Nov;
8(1):117.
PMID: 36316318
Long noncoding RNAs (lncRNAs) are usually 5' capped and 3' polyadenylated, similar to most typical mRNAs. However, recent studies revealed a type of snoRNA-related lncRNA with unique structures, leading to...
9.
Deng Y, Xu Q, Chen T, Ming J, Wang Y, Mao L, et al.
Phytomedicine
. 2022 Jun;
104:154241.
PMID: 35749827
Background: Non-alcoholic steatohepatitis (NASH) has replaced viral hepatitis as the main driver of the rising morbidity and mortality associated with cirrhosis and liver cancer worldwide, while no FDA-approved therapies are...
10.
Han C, Sun L, Luo X, Pan Q, Sun Y, Zeng Z, et al.
Cell Rep
. 2022 Mar;
38(13):110421.
PMID: 35354054
Small nucleolar RNAs (snoRNAs) are commonly acknowledged as a class of homogeneous non-coding RNAs that guide ribosomal RNA modifications. However, snoRNAs referred to as orphans have largely unknown functions. Here,...