Tian-Min Fu
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Explore the profile of Tian-Min Fu including associated specialties, affiliations and a list of published articles.
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47
Citations
1680
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Recent Articles
11.
Shen Z, Yang X, Xia S, Huang W, Taylor D, Nakanishi K, et al.
Nature
. 2023 Jul;
621(7977):154-161.
PMID: 37494956
Although eukaryotic and long prokaryotic Argonaute proteins (pAgos) cleave nucleic acids, some short pAgos lack nuclease activity and hydrolyse NAD(P) to induce bacterial cell death. Here we present a hierarchical...
12.
Rish A, Shen Z, Chen Z, Zhang N, Zheng Q, Fu T
Nat Commun
. 2023 Jun;
14(1):3549.
PMID: 37322069
The Holliday junction (HJ) is a DNA intermediate of homologous recombination, involved in many fundamental physiological processes. RuvB, an ATPase motor protein, drives branch migration of the Holliday junction with...
13.
Uddin N, Binzel D, Shu D, Fu T, Guo P
Acta Pharm Sin B
. 2023 May;
13(4):1383-1399.
PMID: 37139430
Exosome is an excellent vesicle for delivery of therapeutics, including RNAi and chemical drugs. The extremely high efficiency in cancer regression can partly be attributed to its fusion mechanism in...
14.
Cheng J, Yu Y, Wang X, Zheng X, Liu T, Hu D, et al.
Nat Commun
. 2023 May;
14(1):2522.
PMID: 37130844
To create a functional neural circuit, neurons develop a molecular identity to discriminate self from non-self. The invertebrate Dscam family and vertebrate Pcdh family are implicated in determining synaptic specificity....
15.
16.
Wang L, Wu D, Robinson C, Fu T
Proc Natl Acad Sci U S A
. 2022 Aug;
119(35):e2203742119.
PMID: 35994636
Vacuolar-type adenosine triphosphatases (V-ATPases) not only function as rotary proton pumps in cellular organelles but also serve as signaling hubs. To identify the endogenous binding partners of V-ATPase, we collected...
17.
Fontana P, Dong Y, Pi X, Tong A, Hecksel C, Wang L, et al.
Science
. 2022 Jun;
376(6598):eabm9326.
PMID: 35679401
INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear membrane of eukaryotic cells that regulates import and export of biomolecules between the nucleus and the cytosol,...
18.
Zhao J, Shi S, Qu H, Keckesova Z, Cao Z, Yang L, et al.
Nat Metab
. 2022 May;
4(6):791.
PMID: 35637348
No abstract available.
19.
Zheng W, Shen C, Wang L, Rawson S, Xie W, Nist-Lund C, et al.
Sci Adv
. 2022 Mar;
8(12):eabm1568.
PMID: 35333573
Human TMEM175, a noncanonical potassium (K) channel in endolysosomes, contributes to their pH stability and is implicated in the pathogenesis of Parkinson's disease (PD). Structurally, the TMEM175 family exhibits an...
20.
Vora S, Fontana P, Mao T, Leger V, Zhang Y, Fu T, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(9).
PMID: 35149555
SARS-CoV-2 is a highly pathogenic virus that evades antiviral immunity by interfering with host protein synthesis, mRNA stability, and protein trafficking. The SARS-CoV-2 nonstructural protein 1 (Nsp1) uses its C-terminal...