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Tian-Jie Lyu

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Articles 11
Citations 16
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Recent Articles
1.
Yang Y, Chen B, Ye X, Ni L, Zhang X, Liu Y, et al.
Cell Rep . 2024 Oct; 43(10):114814. PMID: 39378153
Fate determination of neural stem cells (NSCs) is crucial for cortex development and is closely linked to neurodevelopmental disorders when gene expression networks are disrupted. The transcriptional corepressor chromodomain Y-like...
2.
Lyu T, Wang J, Zhao F, Sun K, Zhao Z, Tian R, et al.
Front Immunol . 2024 Oct; 15:1461450. PMID: 39364412
Computed tomography (CT) scans and magnetic resonance imaging (MRI) are commonly utilized to detect brain gliomas and central nervous system inflammation diseases. However, there are instances where depending solely on...
3.
Lyu T, Qiu X, Wang Y, Zhang L, Dai Y, Wang X, et al.
MedComm (2020) . 2024 Jul; 5(7):e652. PMID: 39006763
Somatic mutations related to clonal hematopoiesis of indeterminate potential (CHIP) are risk factors for stroke. The impact of , the most mutated gene in CHIP, on clinical functional outcomes of...
4.
Lyu T, Ma J, Zhang X, Xie G, Liu C, Du J, et al.
Mol Psychiatry . 2024 Jan; 29(5):1253-1264. PMID: 38228891
The pathophysiology of autism spectrum disorders (ASDs) is causally linked to postsynaptic scaffolding proteins, as evidenced by numerous large-scale genomic studies [1, 2] and in vitro and in vivo neurobiological...
5.
Sun Z, Waybright J, Beldar S, Chen L, Foley C, Norris-Drouin J, et al.
Adv Sci (Weinh) . 2023 Sep; 10(25):e2304061. PMID: 37667836
No abstract available.
6.
Sun Z, Waybright J, Beldar S, Chen L, Foley C, Norris-Drouin J, et al.
Adv Sci (Weinh) . 2022 Feb; 9(10):e2104317. PMID: 35119221
Epigenetic modifications are involved in the onset, development, and maintenance of pain; however, the precise epigenetic mechanism underlying pain regulation remains elusive. Here it is reported that the epigenetic factor...
7.
Gu H, Yang K, Yang X, Wang C, Lyu T, Zhao X, et al.
Ann Transl Med . 2021 Sep; 9(15):1224. PMID: 34532361
Background: Lowering low-density lipoprotein cholesterol (LDL-C) is crucial for secondary stroke prevention in stroke patients with preexisting cardiovascular diseases (CVD) or cerebrovascular diseases (CeVD). However, data on attainment of guideline-recommended...
8.
Wang W, Lyu T, Li Z
Neuropsychiatr Dis Treat . 2021 Sep; 17:2811-2818. PMID: 34471355
Cell polarity is an intrinsic property of epithelial cells regulated by scaffold proteins. The CRB (crumbs) complex is known to play a predominant role in the dynamic cooperative network of...
9.
Li J, Li Z, Lyu T, Cheng S, Pu Y, Wang Y
Neurosci Bull . 2021 Jun; 37(9):1361-1364. PMID: 34164776
No abstract available.
10.
Dong C, Liu Y, Lyu T, Beldar S, Lamb K, Tempel W, et al.
Cell Chem Biol . 2020 May; 27(7):827-838.e7. PMID: 32470319
The CDY (chromodomain on the Y) proteins play an essential role in normal spermatogenesis and brain development. Dysregulation of their expression has been linked to male infertility and various neurological...