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Thopisang Motlou

Explore the profile of Thopisang Motlou including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 237
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Recent Articles
1.
Richardson S, Mzindle N, Motlou T, Manamela N, van der Mescht M, Lambson B, et al.
J Virol . 2024 Jul; 98(7):e0067824. PMID: 38953380
Importance: The continued evolution of SARS-CoV-2 has resulted in a number of variants of concern. Of these, the Omicron sublineage is the most immune evasive. Within Omicron, the BA.4/5 sublineage...
2.
Moyo-Gwete T, Richardson S, Keeton R, Hermanus T, Spencer H, Manamela N, et al.
PLoS Pathog . 2023 Nov; 19(11):e1011772. PMID: 37943890
The impact of previous SARS-CoV-2 infection on the durability of Ad26.COV2.S vaccine-elicited responses, and the effect of homologous boosting has not been well explored. We followed a cohort of healthcare...
3.
Moyo-Gwete T, Richardson S, Keeton R, Hermanus T, Spencer H, Manamela N, et al.
medRxiv . 2023 Mar; PMID: 36993404
The impact of previous SARS-CoV-2 infection on the durability of Ad26.COV2.S vaccine-elicited responses, and the effect of homologous boosting has not been well explored. We followed a cohort of healthcare...
4.
OKennedy M, Abolnik C, Smith T, Motlou T, Goosen K, Sepotokele K, et al.
Vaccine . 2023 Mar; 41(13):2261-2269. PMID: 36868876
The outbreak of the SARS-CoV-2 global pandemic heightened the pace of vaccine development with various vaccines being approved for human use in a span of 24 months. The SARS-CoV-2 trimeric...
5.
Madhi S, Kwatra G, Richardson S, Koen A, Baillie V, Cutland C, et al.
Lancet Infect Dis . 2022 Oct; 23(3):295-306. PMID: 36273491
Background: COVID-19 vaccine rollout is lagging in Africa, where there has been a high rate of SARS-CoV-2 infection. We aimed to evaluate the effect of SARS-CoV-2 infection before vaccination with...
6.
Margolin E, Allen J, Verbeek M, Chapman R, Meyers A, van Diepen M, et al.
Biotechnol Bioeng . 2022 Jul; 119(10):2919-2937. PMID: 35781691
Heterologous glycoprotein production relies on host glycosylation-dependent folding. When the biosynthetic machinery differs from the usual expression host, there is scope to remodel the assembly pathway to enhance glycoprotein production....
7.
Kitchin D, Richardson S, van der Mescht M, Motlou T, Mzindle N, Moyo-Gwete T, et al.
Cell Rep Med . 2022 Apr; 3(3):100535. PMID: 35474744
The Janssen (Johnson & Johnson) Ad26.COV2.S non-replicating viral vector vaccine has been widely deployed for COVID-19 vaccination programs in resource-limited settings. Here we confirm that neutralizing and binding antibody responses...
8.
Richardson S, Madzorera V, Spencer H, Manamela N, van der Mescht M, Lambson B, et al.
Cell Host Microbe . 2022 Apr; 30(6):880-886.e4. PMID: 35436444
The SARS-CoV-2 Omicron variant escapes neutralizing antibodies elicited by vaccines or infection. However, whether Omicron triggers cross-reactive humoral responses to other variants of concern (VOCs) remains unknown. We used plasma...
9.
Chibwana M, Moyo-Gwete T, Kwatra G, Mandolo J, Hermanaus T, Motlou T, et al.
BMC Med . 2022 Mar; 20(1):128. PMID: 35346184
Background: Binding and neutralising anti-Spike antibodies play a key role in immune defence against SARS-CoV-2 infection. Since it is known that antibodies wane with time and new immune-evasive variants are...
10.
Guarido M, Motlou T, Riddin M, MacIntyre C, Manyana S, Johnson T, et al.
Emerg Infect Dis . 2021 Nov; 27(12):3142-3146. PMID: 34808093
Shuni virus is associated with neurologic and febrile illness in animals and humans. To determine potential vectors, we collected mosquitoes in South Africa and detected the virus in species of...