Thomas Z Armel
Overview
Explore the profile of Thomas Z Armel including associated specialties, affiliations and a list of published articles.
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5
Citations
187
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0
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Recent Articles
1.
Garg A, Lohmueller J, Silver P, Armel T
Nucleic Acids Res
. 2012 May;
40(15):7584-95.
PMID: 22581776
The ability to engineer biological circuits that process and respond to complex cellular signals has the potential to impact many areas of biology and medicine. Transcriptional activator-like effectors (TALEs) have...
2.
Lohmueller J, Armel T, Silver P
Nucleic Acids Res
. 2012 Feb;
40(11):5180-7.
PMID: 22323524
The ability to perform molecular-level computation in mammalian cells has the potential to enable a new wave of sophisticated cell-based therapies and diagnostics. To this end, we developed a Boolean...
3.
Armel T, Leinwand L
Biochem Biophys Res Commun
. 2009 Nov;
391(1):352-6.
PMID: 19913502
Hypertrophic cardiomyopathy (HCM) is a common, autosomal dominant disorder primarily characterized by left ventricular hypertrophy and is the leading cause of sudden cardiac death in youth. HCM is caused by...
4.
Armel T, Leinwand L
J Mol Cell Cardiol
. 2009 Oct;
48(5):1007-13.
PMID: 19854198
To date, more than 230 disease-causing mutations have been linked to the slow/cardiac muscle myosin gene, beta-MyHC (MYH7). Most of these mutations are located in the globular head region of...
5.
Armel T, Leinwand L
Proc Natl Acad Sci U S A
. 2009 Apr;
106(15):6291-6.
PMID: 19336582
Myosin storage myopathy (MSM) is a congenital myopathy characterized by the presence of subsarcolemmal inclusions of myosin in the majority of type I muscle fibers, and has been linked to...