Thomas Vuillemin
Overview
Explore the profile of Thomas Vuillemin including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
7
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Recent Articles
1.
Romann P, Vuillemin T, Pavone S, Jordan M, Perilleux A, Souquet J, et al.
J Biotechnol
. 2024 Feb;
383:73-85.
PMID: 38340899
Controlling high-mannose (HM) content of therapeutic proteins during process intensification, reformulation for subcutaneous delivery, antibody-drug conjugate or biosimilar manufacturing represents an ongoing challenge. Even though a range of glycosylation levers...
2.
Bruhlmann D, Vuillemin T, Satwekar A, Galano E, Palmese A, DAngelo A, et al.
Biotechnol Bioeng
. 2019 Jan;
116(5):1017-1028.
PMID: 30659587
Glycosylation, a critical product quality attribute, may affect the efficacy and safety of therapeutic proteins in vivo. Chinese hamster ovary fed-batch cell culture batches yielded consistent glycoprofiles of a Fc-fusion...
3.
Bruhlmann D, Muhr A, Parker R, Vuillemin T, Bucsella B, Kalman F, et al.
J Biotechnol
. 2017 May;
252:32-42.
PMID: 28465212
Glycosylation plays a pivotal role in pharmacokinetics and protein physiochemical characteristics. In particular, effector functions including antibody-dependent cell-mediated cytotoxicity (ADCC) can be desired, and it has been described that high-mannose...