Thomas Perrier
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Explore the profile of Thomas Perrier including associated specialties, affiliations and a list of published articles.
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11
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109
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Recent Articles
1.
Lollo G, Matha K, Bocchiardo M, Bejaud J, Marigo I, Virgone-Carlotta A, et al.
J Drug Target
. 2018 Nov;
27(5-6):634-645.
PMID: 30461322
In this work, a novel lipophilic 5-fluorouracil (5-FU) derivative was synthesised and encapsulated into lipid nanocapsules (LNC). 5-FU was modified with lauric acid to give a lipophilic mono-lauroyl-derivative (5-FU-C12, MW...
2.
Nguyen H, Munnier E, Perse X, Vial F, Yvergnaux F, Perrier T, et al.
J Pharm Sci
. 2016 Aug;
105(10):3191-3198.
PMID: 27519648
In this study, we evaluated the potential of lipid nanocapsules (LNC) of 120 nm as drug nanocarriers to treat skin diseases. As a model molecule, we encapsulated the fluorescent dye...
3.
Roy S, Glueckert R, Johnston A, Perrier T, Bitsche M, Newman T, et al.
Nanomedicine (Lond)
. 2011 Nov;
7(1):55-63.
PMID: 22106854
Unlabelled: Hearing loss is a very significant health problem. The methods currently available for inner ear drug delivery are limited and a noninvasive cell-specific drug delivery strategy needs to be...
4.
Perrier T, Fouchet F, Bastiat G, Saulnier P, Benoit J
Int J Pharm
. 2011 Aug;
419(1-2):266-70.
PMID: 21839821
Lipidic NanoCapsules (LNCs) were prepared via an emulsion phase inversion method. Nanoparticles with hydrodynamic diameter of 25, 50 and 100 nm were easily obtained. Their surfaces are covered with short...
5.
Zhang Y, Zhang W, Lobler M, Schmitz K, Saulnier P, Perrier T, et al.
Int J Pharm
. 2010 Nov;
404(1-2):211-9.
PMID: 21075187
Nanoparticle-mediated drug delivery represents the future in terms of treating inner ear diseases. Lipid core nanocapsules (LNCs), 50 nm in size, were shown to pass though the round window membrane...
6.
Perrier T, Saulnier P, Benoit J
Chemistry
. 2010 Aug;
16(38):11516-29.
PMID: 20803579
In the field of nanometre-sized drug-delivery systems, a wide range of colloidal systems have been created in recent decades. All of the systems have a similar global structure, that is,...
7.
Perrier T, Saulnier P, Fouchet F, Lautram N, Benoit J
Int J Pharm
. 2010 Jul;
396(1-2):204-9.
PMID: 20600733
Over the last decade, Lipid NanoCapsules (LNCs) have been intensively used as effective drug delivery systems; they are classically prepared using a phase-inversion method. Following formulation of the LNCs, the...
8.
Scheper V, Wolf M, Scholl M, Kadlecova Z, Perrier T, Klok H, et al.
Nanomedicine (Lond)
. 2009 Aug;
4(6):623-35.
PMID: 19663591
Aim: Treatment of sensorineural hearing loss could be advanced using novel drug carriers such as hyperbranched polylysine (HBPL) or lipid nanocapsules (LNCs). This study examined HBPL and LNCs for their...
9.
Zou J, Saulnier P, Perrier T, Zhang Y, Manninen T, Toppila E, et al.
J Biomed Mater Res B Appl Biomater
. 2008 Apr;
87(1):10-8.
PMID: 18437698
Hearing loss is a major public health problem, and its treatment with traditional therapy strategies is often unsuccessful due to limited drug access deep in the temporal bone. Multifunctional nanoparticles...
10.
Ananchenko G, Udachin K, Dubes A, Ripmeester J, Perrier T, Coleman A
Angew Chem Int Ed Engl
. 2006 Jan;
45(10):1585-8.
PMID: 16444790
No abstract available.