Thomas P Flagg
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Explore the profile of Thomas P Flagg including associated specialties, affiliations and a list of published articles.
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36
Citations
734
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Recent Articles
1.
Currie T, Engler M, Krauthamer V, Scott J, Deuster P, Flagg T
Nutrients
. 2023 Mar;
15(5).
PMID: 36904203
Optimal nutrition is imperative for psychological health. Oxidative stress and inflammation are underlying etiologies for alterations in psychological health. Warfighters are at risk of health concerns such as depression due...
2.
Vasudevan N, Soni D, Moffett J, Krishnan J, Appu A, Ghoshal S, et al.
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835088
The coordination of cellular biological processes is regulated in part via metabolic enzymes acting to match cellular metabolism to current conditions. The acetate activating enzyme, acyl-coenzyme A synthetase short-chain family...
3.
Klein M, Krantz M, Fatima N, Watters A, Colon-Sanchez D, Geiger R, et al.
J Am Heart Assoc
. 2022 Jun;
11(11):e023482.
PMID: 35658478
Background Methadone is associated with a disproportionate risk of sudden death and ventricular tachyarrhythmia despite only modest inhibition of delayed rectifier K current () the principal mechanism of drug-associated arrhythmia....
4.
Currie T, Engler M, Olsen C, Krauthamer V, Scott J, Deuster P, et al.
Molecules
. 2022 May;
27(9).
PMID: 35566133
Oxidative stress is a key underlying factor in cognitive decline and atherosclerosis. Oxidative stress occurs at the cellular level with an imbalance between reactive oxygen species and reactive nitrogen species...
5.
Geiger R, Klein M, Fatima N, Goldstein R, Krantz M, Haigney M, et al.
JACC Clin Electrophysiol
. 2020 Dec;
6(14):1860-1862.
PMID: 33357585
No abstract available.
6.
Geiger R, Fatima N, Schooley Jr J, Smyth J, Haigney M, Flagg T
Physiol Rep
. 2020 Dec;
8(24):e14675.
PMID: 33356020
We recently discovered that the histone deacetylase inhibitor, trichostatin A (TSA), increases expression of the sulfonylurea receptor 2 (SUR2; Abcc9) subunit of the ATP-sensitive K (K ) channel in HL-1...
7.
Khayrullina G, Moritz K, Schooley J, Fatima N, Viollet C, McCormack N, et al.
Skelet Muscle
. 2020 May;
10(1):16.
PMID: 32384912
Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by loss of alpha motor neurons and skeletal muscle atrophy. The disease is caused by mutations of the SMN1 gene that...
8.
Krantz M, Flagg T, Haigney M
Circulation
. 2020 Apr;
141(17):1424-1426.
PMID: 32339043
No abstract available.
9.
Goldstein R, Klein M, Ouimet S, Shou M, Hood M, Flagg T, et al.
J Card Fail
. 2019 Aug;
25(10):828-836.
PMID: 31461671
Objectives: To evaluate possible treatment-related hemodynamic changes, we administered ranolazine or mexiletine to swine with heart failure (HF) and to controls. Background: Ranolazine and mexiletine potently inhibit depolarizing late Na...
10.
Klein M, Haigney M, Mehler P, Fatima N, Flagg T, Krantz M
JACC Clin Electrophysiol
. 2018 May;
2(7):784-789.
PMID: 29759761
Objectives: The aim of this study was to determine the in vitro electrophysiological properties of loperamide. The authors' hypothesis was that loperamide is a potent blocker of the current carried...