Thomas Nyalile
Overview
Explore the profile of Thomas Nyalile including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
68
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Liu P, Ponnienselvan K, Nyalile T, Oikemus S, Joynt A, Iyer S, et al.
Nat Biotechnol
. 2024 Sep;
PMID: 39322763
In primary cell types, intracellular deoxynucleotide triphosphate (dNTP) levels are tightly regulated in a cell cycle-dependent manner. We report that prime editing efficiency is increased by mutations that improve the...
2.
Ponnienselvan K, Liu P, Nyalile T, Oikemus S, Joynt A, Kelly K, et al.
bioRxiv
. 2023 Oct;
PMID: 37904991
Prime editing efficiency is modest in cells that are quiescent or slowly proliferating where intracellular dNTP levels are tightly regulated. MMLV-reverse transcriptase - the prime editor polymerase subunit - requires...
3.
Ponnienselvan K, Liu P, Nyalile T, Oikemus S, Maitland S, Lawson N, et al.
Nucleic Acids Res
. 2023 May;
51(13):6966-6980.
PMID: 37246708
Prime editing systems have enabled the incorporation of precise edits within a genome without introducing double strand breaks. Previous studies defined an optimal primer binding site (PBS) length for the...
4.
Yurkovetskiy L, Egri S, Kurhade C, Diaz-Salinas M, Jaimes J, Nyalile T, et al.
bioRxiv
. 2023 Apr;
PMID: 37034621
SARS-CoV-2 variants bearing complex combinations of mutations that confer increased transmissibility, COVID-19 severity, and immune escape, were first detected after S:D614G had gone to fixation, and likely originated during persistent...
5.
Petros B, Paull J, Tomkins-Tinch C, Loftness B, DeRuff K, Nair P, et al.
Med
. 2022 Oct;
3(12):883-900.e13.
PMID: 36198312
Background: Universities are vulnerable to infectious disease outbreaks, making them ideal environments to study transmission dynamics and evaluate mitigation and surveillance measures. Here, we analyze multimodal COVID-19-associated data collected during...
6.
Chen J, Qiu M, Ye Z, Nyalile T, Li Y, Glass Z, et al.
Sci Adv
. 2021 May;
7(19).
PMID: 33952519
In situ vaccination is a promising strategy for cancer immunotherapy owing to its convenience and the ability to induce numerous tumor antigens. However, the advancement of in situ vaccination techniques...
7.
Yurkovetskiy L, Wang X, Pascal K, Tomkins-Tinch C, Nyalile T, Wang Y, et al.
bioRxiv
. 2020 Jul;
PMID: 32637944
The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus worldwide in a matter of months. Here we show that D614G was more infectious than the ancestral form on...