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Thomas N Y Kwong

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Articles 13
Citations 693
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Recent Articles
1.
Kang X, Ng S, Liu C, Lin Y, Zhou Y, Kwong T, et al.
EBioMedicine . 2023 Jun; 93:104670. PMID: 37343363
Background: Obesity is a risk factor for colorectal cancer (CRC). The role of gut microbiota in mediating the cancer-promoting effect of obesity is unknown. Methods: Azoxymethane (AOM)-treated, Apc and germ-free...
2.
Wong O, Lam A, Or B, Mo F, Shea C, Lai K, et al.
Sci Rep . 2022 Jun; 12(1):10659. PMID: 35739175
Emerging evidence of an altered gut microbiome in autism spectrum disorder (ASD) suggests a pathomechanism through the gut-brain axis despite the inconsistent microbiome profile reported across studies. One of the...
3.
Guo C, Kwong T, Mak J, Zhang L, Lui G, Wong G, et al.
Emerg Infect Dis . 2021 Nov; 27(12). PMID: 34812719
No abstract available.
4.
Kong K, Kwong T, Chan H, Wong K, Wong S, Chaparala A, et al.
Emerg Microbes Infect . 2020 Mar; 9(1):631-638. PMID: 32183606
infection (CDI) is a common cause of nosocomial diarrhea and can sometimes lead to pseudo-membranous colitis and toxic megacolon. We previously reported that the PCR ribotype 002 was a common...
5.
Zhang Y, Zhang L, Yang L, Vong C, Chan K, Wu W, et al.
Sci Adv . 2019 Feb; 5(1):eaau9650. PMID: 30746470
A rapid, direct, and low-cost method for detecting bacterial toxins associated with common gastrointestinal diseases remains a great challenge despite numerous studies and clinical assays. Motion-based detection through tracking the...
6.
Kwong T, Wu W, Wong S
Gastroenterology . 2018 Nov; 156(1):292. PMID: 30472232
No abstract available.
7.
Wong S, Kwong T, Wu C, Yu J
Semin Cancer Biol . 2018 May; 55:28-36. PMID: 29782923
The involvement of microorganisms in cancer has been increasing recognized. Collectively, microorganisms have been estimated to account for ∼20% of all cancers worldwide. Recent advances in metagenomics and bioinformatics have...
8.
Kwong T, Wang X, Nakatsu G, Chow T, Tipoe T, Dai R, et al.
Gastroenterology . 2018 May; 155(2):383-390.e8. PMID: 29729257
Background & Aims: Colorectal cancer (CRC) development has been associated with increased proportions of Bacteroides fragilis and certain Streptococcus, Fusobacterium, and Peptostreptococcus species in the intestinal microbiota. We investigated associations...
9.
Chan H, Zhao S, Zhang L, Ho J, Leung C, Wong W, et al.
J Cell Mol Med . 2018 Feb; 22(4):2469-2477. PMID: 29383879
Toxin B (TcdB) is a major pathogenic factor of Clostridum difficile. However, the mechanism by which TcdB exerts its cytotoxic action in host cells is still not completely known. Herein,...
10.
Chow V, Kwong T, So E, Ho Y, Wong S, Lai R, et al.
Sci Rep . 2017 Dec; 7(1):17218. PMID: 29222426
Incidence of Clostridium difficile infection (CDI) is rapidly increasing and it poses a major health burden globally. However, data regarding the epidemiology of CDI in Asia are limited. We aimed...