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Thomas M Jenkins

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Articles 56
Citations 717
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Recent Articles
1.
Shil R, Seed A, Franklyn N, Sargent B, Wood G, Huang Y, et al.
Sci Rep . 2025 Jan; 15(1):3443. PMID: 39870668
It is established that patients hospitalised with COVID-19 often have ongoing morbidity affecting activity of daily living (ADL), employment, and mental health. However, little is known about the relative outcomes...
2.
Alam A, Webb G, Collie C, Mariathasan S, Huang Y, Hilton O, et al.
Clin Med (Lond) . 2024 Sep; 24(5):100241. PMID: 39244036
Reproducible and standardised neurological assessment scales are important in quantifying research outcomes. These scales are often performed by non-neurologists and/or non-clinicians and must be robust, quantifiable, reproducible and comparable to...
3.
Payne T, Appleby M, Buckley E, van Gelder L, Mullish B, Sassani M, et al.
Mov Disord . 2023 May; 38(8):1493-1502. PMID: 37246815
Background: Rescue of mitochondrial function is a promising neuroprotective strategy for Parkinson's disease (PD). Ursodeoxycholic acid (UDCA) has shown considerable promise as a mitochondrial rescue agent across a range of...
4.
Rakusa M, Ozturk S, Moro E, Helbok R, Bassetti C, Beghi E, et al.
Eur J Neurol . 2022 Apr; 29(8):2163-2172. PMID: 35460319
Background And Purpose: Health risks associated with SARS-CoV-2 infection are undisputed. Moreover, the capability of vaccination to prevent symptomatic, severe, and fatal COVID-19 is recognized. There is also early evidence...
5.
Thompson A, Gray E, Verber N, Bobeva Y, Lombardi V, Shepheard S, et al.
Brain Commun . 2022 Feb; 4(1):fcac029. PMID: 35224491
The routine clinical integration of individualized objective markers of disease activity in those diagnosed with the neurodegenerative disorder amyotrophic lateral sclerosis is a key requirement for therapeutic development. A large,...
6.
Chan Y, Alix J, Neuwirth C, Barkhaus P, Castro J, Jenkins T, et al.
Muscle Nerve . 2021 Oct; 65(2):203-210. PMID: 34687220
Introduction/aims: The motor unit size index (MUSIX) may provide insight into reinnervation patterns in diseases such as amyotrophic lateral sclerosis (ALS). However, it is not known whether MUSIX detects clinically...
7.
Anton A, Mead R, Shaw P, Edden R, Bigley J, Jenkins T, et al.
J Magn Reson Imaging . 2021 Jul; 55(2):435-442. PMID: 34322948
Background: Glutathione (GSH) is an important brain antioxidant and a number of studies have reported its measurement by edited and nonedited localized H spectroscopy techniques within a range of applications...
8.
Shepheard S, Parker M, Cooper-Knock J, Verber N, Tuddenham L, Heath P, et al.
J Neurol Neurosurg Psychiatry . 2021 Feb; 92(5):510-518. PMID: 33589474
Objective: The clinical utility of routine genetic sequencing in amyotrophic lateral sclerosis (ALS) is uncertain. Our aim was to determine whether routine targeted sequencing of 44 ALS-relevant genes would have...
9.
Sellner J, Jenkins T, von Oertzen T, Bassetti C, Beghi E, Bereczki D, et al.
Eur J Neurol . 2021 Jan; 28(11):3849-3855. PMID: 33460486
Coronavirus disease 2019 (COVID-19), a multi-organ disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to challenge health and care systems around the globe. The pandemic has disrupted...
10.
Sassani M, Alix J, McDermott C, Baster K, Hoggard N, Wild J, et al.
Brain . 2021 Jan; 143(12):3603-3618. PMID: 33439988
Mitochondrial dysfunction is postulated to be central to amyotrophic lateral sclerosis (ALS) pathophysiology. Evidence comes primarily from disease models and conclusive data to support bioenergetic dysfunction in vivo in patients...