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Thomas Kirchner

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Articles 343
Citations 11168
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Recent Articles
1.
Geyer F, Ritter A, Kinn-Gurzo S, Faehling T, Li J, Jarosch A, et al.
Cancer Commun (Lond) . 2025 Mar; PMID: 40088092
No abstract available.
2.
Santos E, Lopez-Navarro J, Suarez-Gutierrez M, Holzwarth N, Albina-Palmarola P, Kirchner T, et al.
Transl Stroke Res . 2024 Apr; PMID: 38622426
Spreading depolarizations (SDs) are a marker of brain injury and have a causative effect on ischemic lesion progression. The hemodynamic responses elicited by SDs are contingent upon the metabolic integrity...
3.
Michl M, Taverna F, Woischke C, Li P, Klauschen F, Kirchner T, et al.
Clin Transl Oncol . 2024 Apr; 26(8):1886-1895. PMID: 38558282
Purpose: Brain metastasis (BM) in colorectal cancer (CRC) is a rare event with poor prognosis. Apart from (K)RAS status and lung and bone metastasis no biomarkers exist to identify patients...
4.
Jacob S, Balonov I, Jurinovic V, Heiliger C, Tschaidse T, Kumbrink J, et al.
Clin Exp Metastasis . 2024 Mar; 41(5):687-697. PMID: 38498101
Rationale: Colorectal Cancer (CRC) represents the third most common type of cancer in Germany and the second most common cancer-related cause of death worldwide. Distant metastases are still the main...
5.
Pretzsch E, Neumann J, Niess H, Pretzsch C, Hofmann F, Kirchner T, et al.
Pathol Res Pract . 2024 Jan; 254:155129. PMID: 38232629
Epithelial-mesenchymal transition (EMT), angiogenesis, cell adhesion and extracellular matrix (ECM) interaction are essential for colorectal cancer (CRC) metastasis. Low grade mucinous neoplasia of the appendix (LAMN) and its advanced state...
6.
Kirchner T, Villringer C, Laufer J
Photoacoustics . 2023 Nov; 33:100556. PMID: 38021292
Photoacoustic imaging through skull bone causes strong attenuation and distortion of the acoustic wavefront, which diminishes image contrast and resolution. As a result, transcranial photoacoustic measurements in humans have been...
7.
Kirchner T, Jiang H, Gao H, Kabutaulaka G, Cheong D, Jiang Y, et al.
Sci Data . 2023 Nov; 10(1):795. PMID: 37951944
This rapid response surveillance project was funded by the National Science Foundation (NSF) to collect "perishable" data on egress behaviors and neighborhood conditions surrounding healthcare centers (HCCs) in New York...
8.
Unger K, Hess J, Link V, Buchner A, Eze C, Li M, et al.
Clin Transl Radiat Oncol . 2023 Mar; 39:100586. PMID: 36935856
Purpose: In prostate cancer, the indication to irradiate the pelvic lymphatic pathways in clinical node-negative patients is solely based on clinical nomograms. To define biological risk patterns of lymphatic spread,...
9.
Lee O, Rodrigues C, Lin S, Luo W, Jones K, Brown D, et al.
Am J Hum Genet . 2023 Feb; 110(3):427-441. PMID: 36787739
Ewing sarcoma (EwS) is a rare bone and soft tissue malignancy driven by chromosomal translocations encoding chimeric transcription factors, such as EWSR1-FLI1, that bind GGAA motifs forming novel enhancers that...
10.
Orth M, Surdez D, Faehling T, Ehlers A, Marchetto A, Grossetete S, et al.
Cell Rep . 2022 Dec; 41(10):111761. PMID: 36476851
Ewing sarcoma (EwS) is characterized by EWSR1-ETS fusion transcription factors converting polymorphic GGAA microsatellites (mSats) into potent neo-enhancers. Although the paucity of additional mutations makes EwS a genuine model to...