Thomas Jespersen
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Explore the profile of Thomas Jespersen including associated specialties, affiliations and a list of published articles.
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Articles
169
Citations
2731
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Recent Articles
11.
Hertel J, Linz B, Isaksen J, Jerltorp K, Leonhardt C, Gottlieb L, et al.
Heart Rhythm
. 2024 Jan;
21(5):622-629.
PMID: 38280622
Background: More than 50% of patients with atrial fibrillation (AF) suffer from sleep disordered breathing (SDB). Obstructive respiratory events contribute to a transient, vagally mediated atrial arrhythmogenic substrate, which is...
12.
Nissen S, Saljic A, Carstensen H, Braunstein T, Melis Hesselkilde E, Kjeldsen S, et al.
Front Cardiovasc Med
. 2023 Nov;
10:1102164.
PMID: 38034369
Background: Second-degree atrioventricular (AV) block at rest is very common in horses. The underlying molecular mechanisms are unexplored, but commonly attributed to high vagal tone. Aim: To assess whether AV...
13.
Dyhr M, Olsen F, Lindberg S, Modin D, Fritz-Hansen T, Pedersen S, et al.
Echocardiography
. 2023 Jun;
40(7):695-702.
PMID: 37335308
Background: Atrial fibrillation (AF) is the most common cardiac arrhythmia following coronary artery bypass grafting (CABG). We hypothesized that measures of left atrial (LA) function would be useful in predicting...
14.
Drag M, Debes K, Franck C, Flethoj M, Lyhne M, Moller J, et al.
Epigenetics
. 2023 Apr;
18(1):2199374.
PMID: 37032646
Profiling of circulating cell-free DNA (cfDNA) by tissue-specific base modifications, such as 5-methylcytosines (5mC), may enable the monitoring of ongoing pathophysiological processes. Nanopore sequencing allows genome-wide 5mC detection in cfDNA...
15.
Carstensen H, Nissen S, Saljic A, Melis Hesselkilde E, van Hunnik A, Hohl M, et al.
J Cardiovasc Transl Res
. 2023 Apr;
16(5):1205-1219.
PMID: 37014465
Atrial fibrillation (AF) is more prevalent in athletes, and currently, the mechanisms are not fully understood. Atrial fibrillation inducibility and stability was investigated in trained and untrained Standardbred racehorses. The...
16.
Hertel J, Jerltorp K, Hansen M, Isaksen J, Sattler S, Linz B, et al.
Front Cardiovasc Med
. 2023 Mar;
10:1139364.
PMID: 36970354
Aim: To propose a standardized workflow for 3D-electroanatomical mapping guided pulmonary vein isolation in pigs. Materials And Methods: Danish female landrace pigs were anaesthetized. Ultrasound-guided puncture of both femoral veins...
17.
Heijman J, Zhou X, Morotti S, Molina C, Abu-Taha I, Tekook M, et al.
Circ Res
. 2023 Mar;
132(9):e116-e133.
PMID: 36927079
Background: Small-conductance Ca-activated K (SK)-channel inhibitors have antiarrhythmic effects in animal models of atrial fibrillation (AF), presenting a potential novel antiarrhythmic option. However, the regulation of SK-channels in human atrial...
18.
Linz B, Hesselkilde E, Skarsfeldt M, Hertel J, Sattler S, Yan Y, et al.
J Cardiovasc Electrophysiol
. 2022 Dec;
34(1):126-134.
PMID: 36482155
Background: Obstructive sleep apnea (OSA) creates a complex substrate for atrial fibrillation (AF), which is refractory to many clinically available pharmacological interventions. We investigated atrial antiarrhythmogenic properties and ventricular electrophysiological...
19.
Nissen S, Saljic A, Kjeldsen S, Jespersen T, Hopster-Iversen C, Buhl R
Animals (Basel)
. 2022 Nov;
12(21).
PMID: 36359039
Second-degree atrioventricular (AV) block is the most common cardiac arrhythmia in horses, affecting 40-90% depending on breed. Usually, the AV blocks occur while the horses are resting and disappear upon...
20.
Ismaili D, Gurr K, Horvath A, Yuan L, Lemoine M, Schulz C, et al.
Cells
. 2022 Aug;
11(15).
PMID: 35954268
The physiological importance of NCX in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is not well characterized but may depend on the relative strength of the current, compared to adult cardiomyocytes,...