Thomas J Matula
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Explore the profile of Thomas J Matula including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Ambekar P, Wang Y, Khokhlova T, Khokhlova T, Thomas G, Thomas G, et al.
IEEE Trans Ultrason Ferroelectr Freq Control
. 2024 Oct;
71:1868-1878.
PMID: 39383065
Large abscesses are walled-off collections of pus and bacteria that often do not respond to antibiotic therapy. Standard of care involves percutaneous placement of indwelling catheter(s) for drainage, a long...
2.
Ambekar P, Wang Y, Khokhlova T, Bruce M, Leotta D, Totten S, et al.
Ultrasound Med Biol
. 2023 Sep;
49(12):2451-2458.
PMID: 37718123
Objective: Bacterial loads can be effectively reduced using cavitation-mediated focused ultrasound, or histotripsy. In this study, gram-negative bacteria (Escherichia coli) in suspension were used as model bacteria to evaluate the...
3.
Schactler S, Scheuerman S, Lius A, Altemeier W, An D, Matula T, et al.
BMC Genomics
. 2023 Aug;
24(1):446.
PMID: 37553584
Background: Disease molecular complexity requires high throughput workflows to map disease pathways through analysis of vast tissue repositories. Great progress has been made in tissue multiomics analytical technologies. To match...
4.
Leotta D, Bruce M, Wang Y, Kucewicz J, Khokhlova T, Chan K, et al.
Ultrasound Med Biol
. 2021 Apr;
47(7):1920-1930.
PMID: 33902954
Abscesses are walled-off collections of infected fluids that often develop as complications in the setting of surgery and trauma. Treatment is usually limited to percutaneous catheterization with a course of...
5.
Matula T, Wang Y, Khokhlova T, Leotta D, Kucewicz J, Brayman A, et al.
Ultrasound Med Biol
. 2020 Nov;
47(3):603-619.
PMID: 33250219
Infected abscesses are walled-off collections of pus and bacteria. They are a common sequela of complications in the setting of surgery, trauma, systemic infections and other disease states. Current treatment...
6.
Khokhlova T, Kucewicz J, Ponomarchuk E, Hunter C, Bruce M, Khokhlova V, et al.
Ultrasound Med Biol
. 2020 May;
46(8):2007-2016.
PMID: 32444137
Large intra-abdominal, retroperitoneal and intramuscular hematomas are common consequences of sharp and blunt trauma and post-surgical bleeds, and often threaten organ failure, compartment syndrome or spontaneous infection. Current therapy options...
7.
Critello C, Pullano S, Matula T, de Franciscis S, Serra R, Fiorillo A
Expert Rev Med Devices
. 2019 Oct;
16(11):931-940.
PMID: 31622557
: Varicose veins are a common disease, causing significant impairment of quality of life to afflicted individuals. Conventional surgery has represented the traditional treatment for years, with significant post-operative complications....
8.
Bomsztyk K, Mar D, Wang Y, Denisenko O, Ware C, Frazar C, et al.
Nucleic Acids Res
. 2019 Mar;
47(12):e69.
PMID: 30927002
Chromatin immunoprecipitation (ChIP) is the most widely used approach for identification of genome-associated proteins and their modifications. We have previously introduced a microplate-based ChIP platform, Matrix ChIP, where the entire...
9.
Matula T, Sapozhnikov O, Ostrovsky L, Brayman A, Kucewicz J, MacConaghy B, et al.
J Acoust Soc Am
. 2018 Aug;
144(1):41.
PMID: 30075653
The isolation and sorting of cells is an important process in research and hospital labs. Most large research and commercial labs incorporate fluorescently or magnetically labeled antibodies adherent to cell...
10.
Brayman A, MacConaghy B, Wang Y, Chan K, Monsky W, Chernikov V, et al.
Ultrasound Med Biol
. 2018 Jun;
44(9):1996-2008.
PMID: 29941214
This study addresses inactivation of E. coli in either 5- or 10-mL volumes, which were 50- to 100-fold greater than used in an earlier study (Brayman et al. 2017). Cells...