Thomas J Gast
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Explore the profile of Thomas J Gast including associated specialties, affiliations and a list of published articles.
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28
Citations
478
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Recent Articles
1.
Parimi V, Elsner A, Papay J, Clark C, Miura M, Gast T
Ophthalmic Physiol Opt
. 2024 Dec;
45(2):480-493.
PMID: 39723623
Purpose: Visual acuity (VA) is a primary outcome measure that defines the success of clinical interventions for retinal diseases such as age-related macular degeneration (AMD) or diabetic macular oedema (DME)....
2.
Keller M, Gast T, King B
Front Ophthalmol (Lausanne)
. 2024 Jul;
3:1229670.
PMID: 38983074
High-resolution imaging methods of the iridocorneal angle (ICA) will lead to enhanced understanding of aqueous humor outflow mechanisms and a characterization of the trabecular meshwork (TM) morphology at the cellular...
3.
Elsner A, Papay J, Parimi V, Jung H, Clark C, Burns S, et al.
Biomed Opt Express
. 2024 Feb;
14(12):6397-6409.
PMID: 38420313
We demonstrate a free-space, trolley-mounted potential vision tester (PVT), designed to study and improve the accuracy of visual acuity (VA) measurements in the aging eye. Key features include a high-resolution...
4.
Parimi V, Elsner A, Gast T, Chen Z, Baskaran K, Alhamami M, et al.
Optom Vis Sci
. 2024 Feb;
101(1):25-36.
PMID: 38350055
Significance: Suspected clinically significant macular edema (SCSME) from exudates differed among ethnic groups in our underserved population. African American and Asian subjects had higher prevalence than Hispanics and non-Hispanic Caucasians,...
5.
Sapoznik K, Gast T, Carmichael-Martins A, Walker B, Warner R, Burns S
Transl Vis Sci Technol
. 2023 Nov;
12(11):16.
PMID: 37962539
Purpose: Adaptive optics scanning laser ophthalmoscopy (AOSLO) enables the visualization and measurement of the retinal microvasculature structure in humans. We investigated the hypothesis that diabetes mellitus (DM) induces remodeling to...
6.
Carmichael-Martins A, Gast T, King B, Walker B, Sobczak M, Burns S
Biomed Opt Express
. 2023 Oct;
14(10):5267-5281.
PMID: 37854570
The trabecular meshwork (TM), located within the iridocorneal angle, is a target for many glaucoma treatments aimed at controlling intraocular pressure. However, structural variations between individuals are poorly understood. We...
7.
Characterization of the human iridocorneal angle using a custom design goniolens with OCT gonioscopy
Carmichael-Martins A, Gast T, Burns S, Walker B, King B
Biomed Opt Express
. 2022 Oct;
13(9):4652-4667.
PMID: 36187241
Intraocular pressure (IOP) is the only modifiable risk factor for glaucoma progression, and many treatments target the trabecular meshwork (TM). Imaging this region is challenging due to optical limitations of...
8.
Elsner A, Walker B, Gilbert R, Parimi V, Papay J, Gast T, et al.
Front Med (Lausanne)
. 2022 Apr;
9:826643.
PMID: 35372411
Purpose: Cones in diabetic patients are at risk due to metabolic and vascular changes. By imaging retinal vessel modeling at high magnification, we reduced its impact on cone distribution measurements....
9.
Warner R, Gast T, Sapoznik K, Carmichael-Martins A, Burns S
Invest Ophthalmol Vis Sci
. 2021 Nov;
62(14):29.
PMID: 34846516
Purpose: The retinal circulation regulates blood flow through various internal and external factors; however, it is unclear how locally these factors act within the retinal microcirculation. We measured the temporal...
10.
Burns S, Elsner A, Gast T
Annu Rev Vis Sci
. 2021 Jun;
7:129-153.
PMID: 34171198
Advances in retinal imaging are enabling researchers and clinicians to make precise noninvasive measurements of the retinal vasculature in vivo. This includes measurements of capillary blood flow, the regulation of...