Thomas J Carew
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Explore the profile of Thomas J Carew including associated specialties, affiliations and a list of published articles.
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54
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1139
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Recent Articles
1.
Miranda P, Mirisis A, Kukushkin N, Carew T
Proc Natl Acad Sci U S A
. 2023 Sep;
120(40):e2300595120.
PMID: 37748056
Transforming growth factor β (TGFβ) is required for long-term memory (LTM) for sensitization in . When LTM is induced using a two-trial training protocol, TGFβ inhibition only blocks LTM when...
2.
Kukushkin N, Tabassum T, Carew T
Proc Natl Acad Sci U S A
. 2022 Sep;
119(40):e2210478119.
PMID: 36161885
Two-trial learning in reveals nonlinear interactions between training trials: A single trial has no effect, but two precisely spaced trials induce long-term memory. Extracellularly regulated kinase (ERK) activity is essential...
3.
Carew T
J Neurosci
. 2021 May;
41(23):4949-4953.
PMID: 33958487
Some of us fortunate enough to have published a paper in in its inaugural year (1981) have been asked to write a Progressions article addressing our views on the significance...
4.
Mirisis A, Kopec A, Carew T
J Neurosci
. 2020 Dec;
41(5):947-959.
PMID: 33298536
Long-term memory (LTM) formation is a critical survival process by which an animal retains information about prior experiences to guide future behavior. In the experimentally advantageous marine mollusk , LTM...
5.
Carew T, Ramaswami M
Neuron
. 2020 Nov;
108(4):590-593.
PMID: 33242428
Neuroscience has an extraordinary opportunity to investigate issues historically addressed by the arts, humanities, and social sciences. As a guide, we suggest three features of meaningful progress in the collaborative...
6.
Alexandrescu A, Carew T
Learn Mem
. 2020 Mar;
27(4):124-129.
PMID: 32179654
The spatial and temporal coordination of growth factor signaling is critical for both presynaptic and postsynaptic plasticity underlying long-term memory formation. We investigated the spatiotemporal dynamics of cysteine-rich neurotrophic factor...
7.
Mirisis A, Carew T
Neurobiol Learn Mem
. 2019 Apr;
161:143-148.
PMID: 30998973
The mechanisms of de novo gene expression and translation of specific gene transcripts have long been known to support long-lasting changes in synaptic plasticity and behavioral long-term memory. In recent...
8.
Mirisis A, Alexandrescu A, Carew T, Kopec A
AIMS Neurosci
. 2016 Nov;
3(3):356-384.
PMID: 27819030
The ability to form long-lasting memories is critical to survival and thus is highly conserved across the animal kingdom. By virtue of its complexity, this same ability is vulnerable to...
9.
Shobe J, Philips G, Carew T
Learn Mem
. 2016 Apr;
23(5):182-8.
PMID: 27084925
In this study, we explore the mechanistic relationship between growth factor signaling and kinase activity that supports the protein synthesis-dependent phase of long-term memory (LTM) consolidation for sensitization ofAplysia Specifically,...
10.
Stough S, Kopec A, Carew T
Neurobiol Learn Mem
. 2015 Aug;
125:47-54.
PMID: 26238564
Cellular changes underlying memory formation can be generated in an activity-dependent manner at specific synapses. Thus an important question concerns the mechanisms by which synaptic signals communicate with the cell...