Thomas H Aldrich
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Explore the profile of Thomas H Aldrich including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
971
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0
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Recent Articles
1.
Daly C, Pasnikowski E, Burova E, Wong V, Aldrich T, Griffiths J, et al.
Proc Natl Acad Sci U S A
. 2006 Oct;
103(42):15491-6.
PMID: 17030814
Angiopoietin (Ang)-2, a context-dependent agonist/antagonist for the vascular-specific Tie2 receptor, is highly expressed by endothelial cells at sites of normal and pathologic angiogenesis. One prevailing model suggests that in these...
2.
Davis S, Papadopoulos N, Aldrich T, Maisonpierre P, Huang T, Kovac L, et al.
Nat Struct Biol
. 2002 Dec;
10(1):38-44.
PMID: 12469114
Angiopoietins are a recently discovered family of angiogenic factors that interact with the endothelial receptor tyrosine kinase Tie2, either as agonists (angiopoietin-1) or as context-dependent agonists/antagonists (angiopoietin-2). Here we show...
3.
Davis S, Aldrich T, Jones P, Acheson A, Compton D, Jain V, et al.
Cell
. 1996 Dec;
87(7):1161-9.
PMID: 8980223
TIE2 is a receptor-like tyrosine kinase expressed almost exclusively in endothelial cells and early hemopoietic cells and required for the normal development of vascular structures during embryogenesis. We report the...
4.
Ip N, McClain J, Barrezueta N, Aldrich T, Pan L, Li Y, et al.
Neuron
. 1993 Jan;
10(1):89-102.
PMID: 8381290
We recently proposed that ciliary neurotrophic factor (CNTF) shares two receptor components with a generally acting cytokine, leukemia inhibitory factor (LIF), but that CNTF also requires a third receptor component...
5.
Squinto S, Stitt T, Aldrich T, Davis S, Blanco S, Radziejewski C, et al.
Cell
. 1991 May;
65(5):885-893.
PMID: 1710174
A variety of findings seem to functionally link brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), while distinguishing both of these factors from the third member of the neurotrophin family, nerve...
6.
Squinto S, Aldrich T, Lindsay R, Morrissey D, Panayotatos N, Bianco S, et al.
Neuron
. 1990 Dec;
5(6):757-66.
PMID: 2176509
The lack of reagents or molecular probes specific for the ciliary neurotrophic factor (CNTF) receptor has hindered characterization of the molecular mechanism(s) by which CNTF influences the proliferation, survival, and...