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Thomas G Smith

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Articles 56
Citations 886
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Recent Articles
1.
Reynolds E, Smith T, Damodaran A, Bhagi-Damodaran A
bioRxiv . 2025 Feb; PMID: 39975345
2-oxoglutarate-dependent non-heme iron hydroxylases offer a direct route to functionalizing C()-H bonds across a diverse range of substrates, making them prime candidates for chemoenzymatic synthetic strategies. We demonstrate the ability...
2.
Pollock R, Britton J, Green N, Hendriksen D, Hodkinson P, Anderton R, et al.
Aerosp Med Hum Perform . 2024 Dec; 95(12):897-901. PMID: 39711414
Introduction: During centrifuge-simulated suborbital spaceplane flights, launch and re-entry frequently cause visual symptoms, and G-induced loss of consciousness can occur. G-related effects may be more prominent during re-entry from microgravity...
3.
Miller-Smith M, Tucker N, Anderton R, Caplin N, Harridge S, Hodkinson P, et al.
Aerosp Med Hum Perform . 2024 Aug; 95(9):716-719. PMID: 39169484
Accessible spaceflight may seem a distant concept. As part of a diverse European Space Agency funded Topical Team, we are working on the physiological feasibility of space missions being undertaken...
4.
Hodkinson P, Smith T
Thorax . 2024 Aug; 79(10):897-898. PMID: 39153861
No abstract available.
5.
Talbot N, Cheng H, Hanstock H, Smith T, Dorrington K, Robbins P
Physiol Rep . 2024 Feb; 12(4):e15944. PMID: 38366054
Maximal exercise capacity is reduced at altitude or during hypoxia at sea level. It has been suggested that this might reflect increased right ventricular afterload due to hypoxic pulmonary vasoconstriction....
6.
Connolly D, Madden L, Edwards V, DOyly T, Harridge S, Smith T, et al.
Aerosp Med Hum Perform . 2023 Sep; 94(10):738-749. PMID: 37726900
Consistent blood biomarkers of hypobaric (altitude) decompression stress remain elusive. Recent laboratory investigation of decompression sickness risk at 25,000 ft (7620 m) enabled evaluation of early pathophysiological responses to exertional...
7.
Connolly D, DOyly T, Harridge S, Smith T, Lee V
Aerosp Med Hum Perform . 2023 Aug; 94(9):666-677. PMID: 37587625
Occurrences of severe decompression sickness (DCS) in military parachutist dispatchers at 25,000 ft (7620 m) prompted revision of exposure guidelines for high altitude parachuting. This study investigated residual risks to...
8.
Li J, Mundhenke T, Smith T, Arnold W, Pomerantz W
Anal Chem . 2023 Mar; 95(14):6071-6079. PMID: 37000984
Accurate temperature measurement via magnetic resonance is valuable for both and analysis of local tissue for evaluating disease pathology and medical interventions. H MRI-based thermometry is used clinically but is...
9.
Smith T, Pollock R, Britton J, Green N, Hodkinson P, Mitchell S, et al.
Aerosp Med Hum Perform . 2023 Feb; 93(12):830-839. PMID: 36757241
High-G acceleration experienced during launch and re-entry of suborbital spaceflights may present challenges for older or medically susceptible participants. A detailed understanding of the associated physiological responses would support the...
10.
Hearn E, Byford J, Wolfe C, Agyei C, Hodkinson P, Pollock R, et al.
Aerosp Med Hum Perform . 2023 Feb; 94(1):42-47. PMID: 36757230
Recently developed wearable monitoring devices can provide arterial oxygen saturation (So₂) measurements, offering potential for use in aerospace operations. Pilots and passengers are already using these technologies, but their performance...