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Thomas Eiermann

Explore the profile of Thomas Eiermann including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 883
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Recent Articles
1.
Martin R, Sospedra M, Eiermann T, Olsson T
Trends Genet . 2021 May; 37(9):784-797. PMID: 34006391
Human leukocyte antigen (HLA)-encoded surface molecules present antigenic peptides to T lymphocytes and play a key role in adaptive immune responses. Besides their physiological role of defending the host against...
2.
Wang J, Jelcic I, Muhlenbruch L, Haunerdinger V, Toussaint N, Zhao Y, et al.
Cell . 2020 Oct; 183(5):1264-1281.e20. PMID: 33091337
The HLA-DR15 haplotype is the strongest genetic risk factor for multiple sclerosis (MS), but our understanding of how it contributes to MS is limited. Because autoreactive CD4 T cells and...
3.
Lehnhardt A, Strecker M, Eiermann T, Marget M, Thaiss F, Nashan B, et al.
Clin Transplant . 2015 Jan; 29(4):359-64. PMID: 25627801
B cells and their regulation by B-cell activating factor BAFF are of growing interest in kidney transplantation (KTx). There is evidence that high serum (s) BAFF leads to increased allosensitization...
4.
Flecken T, Schmidt N, Hild S, Gostick E, Drognitz O, Zeiser R, et al.
Hepatology . 2013 Sep; 59(4):1415-26. PMID: 24002931
Unlabelled: Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide with a poor prognosis and limited therapeutic options. To aid the development of novel immunological interventions, we studied the...
5.
Nitschke K, Barriga A, Schmidt J, Timm J, Viazov S, Kuntzen T, et al.
J Hepatol . 2013 Aug; 60(1):22-9. PMID: 23978718
Background & Aims: HLA-B*27 is associated with spontaneous HCV genotype 1 clearance. HLA-B*27-restricted CD8+ T cells target three NS5B epitopes. Two of these epitopes are dominantly targeted in the majority...
6.
Mohme M, Hotz C, Stevanovic S, Binder T, Lee J, Okoniewski M, et al.
Brain . 2013 Jun; 136(Pt 6):1783-98. PMID: 23739916
The HLA-DR15 haplotype confers the largest part of the genetic risk to develop multiple sclerosis, a prototypic CD4+ T cell-mediated autoimmune disease. The mechanisms how certain HLA-class II molecules functionally...
7.
Toth I, Le A, Hartjen P, Thomssen A, Matzat V, Lehmann C, et al.
J Leukoc Biol . 2013 May; 94(4):551-61. PMID: 23709688
Recent studies indicate that murine Tregs highly express the ENTDP1, as well as the 5'-NT and thereby, suppress Teff function by extracellular adenosine production. Furthermore, CD73 seems to play a...
8.
Koch M, Graser C, Lehnhardt A, Pollok J, Kroger N, Verboom M, et al.
Transpl Int . 2013 May; 26(8):e64-8. PMID: 23672514
Although donor-specific lymphocytotoxic antibodies are regarded as a contraindication for kidney transplantation (KTx), the data available for liver or combined liver or kidney transplantation (cLKTx) are scarce. Here, we report...
9.
Awa W, Boehm B, Rosinger S, Achenbach P, Ziegler A, Krause S, et al.
Pediatr Diabetes . 2013 May; 14(8):562-74. PMID: 23627341
Aim: To characterize the clinical and immunological features of HLA-typed youth with pediatric onset of type 2 diabetes mellitus (T2DM). Method: One hundred and seven patients with clinically diagnosed T2DM...
10.
Sierich H, Eiermann T
Curr Protoc Immunol . 2013 Feb; Chapter 14:Unit 14.32.. PMID: 23392637
Natural killer (NK) cells play an important role in the innate immune system by eliminating infected and mutated cells. Their cytotoxic capacities vary markedly among individuals. The cytotoxic activity can...