Thomas E Ouldridge
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Explore the profile of Thomas E Ouldridge including associated specialties, affiliations and a list of published articles.
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56
Citations
1285
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Recent Articles
1.
Guntoro J, Qureshi B, Ouldridge T
J Chem Phys
. 2025 Feb;
162(5).
PMID: 39918127
Templated copolymerization, in which information stored in the sequence of a heteropolymer template is copied into another polymer product, is the mechanism behind all known methods of genetic information transfer....
2.
Poole W, Ouldridge T, Gopalkrishnan M
J R Soc Interface
. 2025 Jan;
22(222):20240373.
PMID: 39837479
Can a micron-sized sack of interacting molecules autonomously learn an internal model of a complex and fluctuating environment? We draw insights from control theory, machine learning theory, chemical reaction network...
3.
Seet I, Ouldridge T, Doye J
Phys Rev E
. 2024 Nov;
110(4-2):045310.
PMID: 39562862
Pipelining is a design technique for logical circuits that allows for higher throughput than circuits in which multiple computations are fed through the system one after the other. It allows...
4.
Wolpert D, Korbel J, Lynn C, Tasnim F, Grochow J, Kardes G, et al.
Proc Natl Acad Sci U S A
. 2024 Oct;
121(45):e2321112121.
PMID: 39471216
The relationship between the thermodynamic and computational properties of physical systems has been a major theoretical interest since at least the 19th century. It has also become of increasing practical...
5.
Smith F, Goertz J, Jurinovic K, Stevens M, Ouldridge T
Nanoscale
. 2024 Sep;
16(37):17624-17637.
PMID: 39235130
Strand displacement reactions underlie dynamic nucleic acid nanotechnology. The kinetic and thermodynamic features of DNA-based displacement reactions are well understood and well predicted by current computational models. By contrast, understanding...
6.
Mukherjee R, Sengar A, Cabello-Garcia J, Ouldridge T
J Am Chem Soc
. 2024 Jul;
146(28):18916-18926.
PMID: 38951503
Kinetic proofreading is used throughout natural systems to enhance the specificity of molecular recognition. At its most basic level, kinetic proofreading uses a supply of chemical fuel to drive a...
7.
Climent-Catala A, Casas-Rodrigo I, Iyer S, Ledesma-Amaro R, Ouldridge T
ACS Synth Biol
. 2023 Nov;
12(12):3754-3765.
PMID: 37991880
Protein-based fluorescent reporters have been widely used to characterize and localize biological processes in living cells. However, these reporters may have certain drawbacks for some applications, such as transcription-based studies...
8.
Seet I, Ouldridge T, Doye J
Phys Rev E
. 2023 Mar;
107(2-1):024134.
PMID: 36932514
Landauer's principle places a fundamental lower limit on the work required to perform a logically irreversible operation. Logically reversible gates provide a way to avoid these work costs and also...
9.
Qureshi B, Juritz J, Poulton J, Beersing-Vasquez A, Ouldridge T
J Chem Phys
. 2023 Mar;
158(10):104906.
PMID: 36922142
Polymers consisting of more than one type of monomer, known as copolymers, are vital to both living and synthetic systems. Copolymerization has been studied theoretically in a number of contexts,...
10.
Hertel S, Spinney R, Xu S, Ouldridge T, Morris R, Lee L
Nucleic Acids Res
. 2022 Jul;
50(14):7829-7841.
PMID: 35880577
The kinetics of DNA hybridization are fundamental to biological processes and DNA-based technologies. However, the precise physical mechanisms that determine why different DNA sequences hybridize at different rates are not...